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- W2034334718 startingPage "16S" @default.
- W2034334718 abstract "Homozygous inheritance of alpha1 antitrypsin deficiency results in very low serum trypsin inhibitory capacity (TIC) and is associated with a high prevalence of a characteristic form of pulmonary emphysema. Heterozygous inheritance of the trait results in intermediate serum TIC values, but may be difficult to identify with certainty by serologic methods. Because of this, the relation between the heterozygous state, serum TIC values and the development of lung disease is difficult to assess. In a previous report we attempted to evaluate the prevalence of intermediate antitrypsin levels in a population of patients with pulmonary disease. In contrast, the present paper correlates the prevalence of pulmonary disease and antitrypsin levels in three different, carefully selected populations." @default.
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- W2034334718 date "1971-05-01" @default.
- W2034334718 modified "2023-09-25" @default.
- W2034334718 title "Alpha1-Antitrypsin Deficiency: Heterozygosity, Intermediate Levels, and Pulmonary Disease" @default.
- W2034334718 doi "https://doi.org/10.1378/chest.59.5_supplement.16s" @default.
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