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- W2034336805 abstract "Summary Collagen type I conformation was studied in skin biopsy samples from 10 normal and 19 spondylarthrotic dogs. Collagen extractability and its content of aldehyde groups were increased in the patients. Both the shape and absorbance of ultraviolet absorption spectra, as well as the alterations of the optical rotatory dispersion in the extracts of the skin of the patients revealed that their collagen is either immature or degraded. The techniques may be useful in cases difficult to diagnoses and also in assessing the benefit of therapy. Zusammenfassung Konformation des Kollagens der Haut bei der Spondylarthrose des Hundes: Die Konformation des Typ I‐Kollagens wurde in Hautbiopsieproben von 10 normalen Hunden sowie von 19 Hunden mit Spondylarthrose untersucht. Die Extrahierbarkeit des Kollagens sowie dessen Gehalt an Aldehydgruppen war bei den Patienten erhöht. Sowohl die Form und das Absorptionsverhalten der Ultraviolettabsorptionsspektren als auch die Veränderungen der Lichtdrehung von Hautextrakten der Patienten belegen, daß das Kollagen bei den Patienten entweder nicht voll ausdifferenziert oder degradiert ist. Die verwendeten Techniken können bei zweifelhafter Diagnose zur Abstützung der Diagnose sowie zur Beurteilung des Therapieerfolges herangezogen werden." @default.
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- W2034336805 date "1987-02-12" @default.
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- W2034336805 title "Skin Collagen Conformation in Canine Spondylarthrosis*" @default.
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- W2034336805 doi "https://doi.org/10.1111/j.1439-0442.1987.tb00302.x" @default.
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