Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034337804> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2034337804 endingPage "2799" @default.
- W2034337804 startingPage "2799" @default.
- W2034337804 abstract "Purpose: To integrate cone beam computed tomography (CBCT) imaging technology into a small animal conformal radiation therapy device (SACRTD) using a six degrees of freedom (6DOF) high accuracy/precision robotic arm. Method and Materials: A 225kV dual focus (0.4mm and 3mm) X-ray tube (GE Seifert Isovolt Titan) is used for both radiation and imaging. An industrial robot (Adept Viper S650) is used for positioning and motion of a small animal for targeted radiation delivery and CBCT imaging with positional repeatability of ±0.020 mm in XYZ direction and angular precision of ±0.2°. A series of 2D-radiographic projection images were recorded in cone beam mode with a flat panel amorphous silicon detector (Perking Elmer), which captures 1024 by 1024 pixels images (200μm pixel size) at a frame rate of 7.5Hz. An open source CBCT reconstruction tool (OSCAR-2, University of Toronto) using Feldkamp-Davis-Kress (FDK) filtered back projection algorithm was employed for CBCT image reconstruction. Results: Initial testing of the CBCT system using phantoms and mice was successful. Radiographs were cropped and downsampled to a spatial resolution of 0.4mm. Reconstructed matrices had dimensions of 181×267×97 voxels with 0.3mm×0.3mm×0.3mm voxel spacing. With the current computer the entire acquisition and reconstruction procedure takes > 7 minutes. The OSCAR-2 algorithm offers various reconstruction filters, but more sophisticated tools specific for small animal imaging are needed to improve the quality of CBCT images. Conclusion: This work demonstrated that a 6DOF robot is an excellent device for moving/rotating a small laboratory animal for acquiring high spatial resolution radiographs with the necessary accuracy and precision for successful CBCT reconstruction. It also demonstrated that an open source CBCT software tool could be adapted to work with the SACRTD. The integration of CBCT imaging into the SACRTD opens new research paths requiring image guided radiation delivery to specific structures/volumes in small animals." @default.
- W2034337804 created "2016-06-24" @default.
- W2034337804 creator A5063256975 @default.
- W2034337804 creator A5065959120 @default.
- W2034337804 creator A5077338603 @default.
- W2034337804 creator A5081161443 @default.
- W2034337804 date "2009-06-01" @default.
- W2034337804 modified "2023-10-16" @default.
- W2034337804 title "TH-C-BRC-08: Integration of Cone Beam CT Imaging and a Small Animal Conformal RT Device Using a 6DOF Robotic Arm" @default.
- W2034337804 doi "https://doi.org/10.1118/1.3182622" @default.
- W2034337804 hasPublicationYear "2009" @default.
- W2034337804 type Work @default.
- W2034337804 sameAs 2034337804 @default.
- W2034337804 citedByCount "0" @default.
- W2034337804 crossrefType "journal-article" @default.
- W2034337804 hasAuthorship W2034337804A5063256975 @default.
- W2034337804 hasAuthorship W2034337804A5065959120 @default.
- W2034337804 hasAuthorship W2034337804A5077338603 @default.
- W2034337804 hasAuthorship W2034337804A5081161443 @default.
- W2034337804 hasConcept C11413529 @default.
- W2034337804 hasConcept C126838900 @default.
- W2034337804 hasConcept C141379421 @default.
- W2034337804 hasConcept C154945302 @default.
- W2034337804 hasConcept C160633673 @default.
- W2034337804 hasConcept C205372480 @default.
- W2034337804 hasConcept C2779813781 @default.
- W2034337804 hasConcept C2989005 @default.
- W2034337804 hasConcept C31601959 @default.
- W2034337804 hasConcept C31972630 @default.
- W2034337804 hasConcept C3261483 @default.
- W2034337804 hasConcept C36454342 @default.
- W2034337804 hasConcept C41008148 @default.
- W2034337804 hasConcept C54170458 @default.
- W2034337804 hasConcept C544519230 @default.
- W2034337804 hasConcept C57493831 @default.
- W2034337804 hasConcept C71924100 @default.
- W2034337804 hasConcept C9267231 @default.
- W2034337804 hasConceptScore W2034337804C11413529 @default.
- W2034337804 hasConceptScore W2034337804C126838900 @default.
- W2034337804 hasConceptScore W2034337804C141379421 @default.
- W2034337804 hasConceptScore W2034337804C154945302 @default.
- W2034337804 hasConceptScore W2034337804C160633673 @default.
- W2034337804 hasConceptScore W2034337804C205372480 @default.
- W2034337804 hasConceptScore W2034337804C2779813781 @default.
- W2034337804 hasConceptScore W2034337804C2989005 @default.
- W2034337804 hasConceptScore W2034337804C31601959 @default.
- W2034337804 hasConceptScore W2034337804C31972630 @default.
- W2034337804 hasConceptScore W2034337804C3261483 @default.
- W2034337804 hasConceptScore W2034337804C36454342 @default.
- W2034337804 hasConceptScore W2034337804C41008148 @default.
- W2034337804 hasConceptScore W2034337804C54170458 @default.
- W2034337804 hasConceptScore W2034337804C544519230 @default.
- W2034337804 hasConceptScore W2034337804C57493831 @default.
- W2034337804 hasConceptScore W2034337804C71924100 @default.
- W2034337804 hasConceptScore W2034337804C9267231 @default.
- W2034337804 hasIssue "6Part27" @default.
- W2034337804 hasLocation W20343378041 @default.
- W2034337804 hasOpenAccess W2034337804 @default.
- W2034337804 hasPrimaryLocation W20343378041 @default.
- W2034337804 hasRelatedWork W1604511055 @default.
- W2034337804 hasRelatedWork W1935924235 @default.
- W2034337804 hasRelatedWork W1976419675 @default.
- W2034337804 hasRelatedWork W2028818020 @default.
- W2034337804 hasRelatedWork W2034905155 @default.
- W2034337804 hasRelatedWork W2056875204 @default.
- W2034337804 hasRelatedWork W2080860377 @default.
- W2034337804 hasRelatedWork W2154337853 @default.
- W2034337804 hasRelatedWork W2164918837 @default.
- W2034337804 hasRelatedWork W4213228110 @default.
- W2034337804 hasVolume "36" @default.
- W2034337804 isParatext "false" @default.
- W2034337804 isRetracted "false" @default.
- W2034337804 magId "2034337804" @default.
- W2034337804 workType "article" @default.