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- W2034341369 abstract "Group data on cognitive outcome in children after successful epilepsy surgery indicate that, except for a significant catchup in developmental function following early operations in children with epileptic regression [ 1 Wyllie E. Comair Y.G. Kotagal P. Raja S. Ruggieri P. Epilepsy surgery in infants. Epilepsia. 1996; 37: 625-637 Crossref PubMed Scopus (193) Google Scholar , 2 Asarnow R.F. LoPresti C. Guthrie D. et al. Developmental outcomes in children receiving resection surgery for medically intractable infantile spasms. Dev Med Child Neurol. 1997; 39: 430-440 Crossref PubMed Scopus (149) Google Scholar , 3 Loddenkemper T. Holland K. Stanford L. Developmental outcome after epilepsy surgery in infancy. Neurology. 2003; 60: A258 Google Scholar , 4 Liu S. An N. Yang H. et al. Pediatric intractable epilepsy syndromes: reason for early surgical intervention. Brain Dev. 2007; 29: 69-78 Abstract Full Text Full Text PDF PubMed Scopus (38) Google Scholar , 5 Roulet-Perez E. Davidoff V. Mayor-Dubois C. et al. Impact of severe epilepsy on development: recovery potential after successful early epilepsy surgery. Epilepsia. 2010; 51: 1266-1276 Crossref PubMed Scopus (54) Google Scholar ], on average, surgery is usually not followed by markedly improved intellectual development [ 5 Roulet-Perez E. Davidoff V. Mayor-Dubois C. et al. Impact of severe epilepsy on development: recovery potential after successful early epilepsy surgery. Epilepsia. 2010; 51: 1266-1276 Crossref PubMed Scopus (54) Google Scholar , 6 Szabó C.A. Wyllie E. Stanford L.D. et al. Neuropsychological effect of temporal lobe resection in preadolescent children with epilepsy. Epilepsia. 1998; 39: 814-819 Crossref PubMed Scopus (95) Google Scholar , 7 Korkman M. Granström M.L. Kantola-Sorsa E. et al. Two-year follow-up of intelligence after pediatric epilepsy surgery. Pediatr Neurol. 2005; 33: 173-178 Abstract Full Text Full Text PDF PubMed Scopus (31) Google Scholar , 8 Sinclair D.B. Wheatley M. Snyder T. Gross D. Ahmed N. Posterior resection for childhood epilepsy. Pediatr Neurol. 2005; 32: 257-263 Abstract Full Text Full Text PDF PubMed Scopus (18) Google Scholar , 9 Battaglia D. Chieffo D. Lettori D. Perrino F. Di Rocco C. Guzzetta F. Cognitive assessment in epilepsy surgery in children. Childs Nerv Syst. 2006; 22: 744-759 Crossref PubMed Scopus (42) Google Scholar , 10 Helmstaedter C. Gleissner U. Clusmann H. Sassen R. Elger C.E. Postsurgical outcome in pediatric patients with epilepsy: a comparison of patients with intellectual disabilities, subaverage intelligence, and average-range intelligence. Epilepsia. 2006; 47: 406-414 Crossref PubMed Scopus (45) Google Scholar , 11 Helmstaedter C. Kockelmann E. Cognitive outcomes in patients with chronic temporal lobe epilepsy. Epilepsia. 2006; 47: 96-98 Crossref PubMed Scopus (107) Google Scholar , 12 Lam W. Cheung M.C. Chan A.S. Chan Y.L. Lam J.M. Effects of illness duration on memory processing of patients with temporal lobe epilepsy. Epilepsia. 2006; 47: 1320-1328 Crossref PubMed Scopus (36) Google Scholar , 13 Gleissner U. Helmstaedter C. Pre-surgical neuropsychological workup in children and intellectually disabled adults with epilepsy. in: Luders H. Textbook of epilepsy surgery. Informa Healthcare, London2008: 834-842 Crossref Google Scholar , 14 Smith M.L. Kelly K. Kadis D.S. et al. Self-reported symptoms of psychological well-being in young adults who underwent resective epilepsy surgery in childhood. Epilepsia. 2011; 52: 891-899 Crossref PubMed Scopus (19) Google Scholar ], but there seem to be no further impairments following surgery [ 15 Lah S. Neuropsychological outcome following focal cortical removal for intractable epilepsy in children. Epilepsy Behav. 2004; 5: 804-817 Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar , 16 Gleissner U. Sassen R. Schramm J. Elger C.E. Helmstaedter C. Greater functional recovery after temporal lobe epilepsy surgery in children. Brain. 2005; 128: 2822-2829 Crossref PubMed Scopus (125) Google Scholar ], along with inconstant gains in attention, processing speed, memory, and bimanual coordination in selected populations [ 17 Jambaquè I. Epilepsies de l'enfant: troubles du développement cognitive et socio-émotionel. Solal, Marseille2008 Google Scholar , 18 Jambaqué I. Dellatolas G. Fohlen M. et al. Memory functions following surgery for temporal lobe epilepsy in children. Neuropsychologia. 2007; 45: 2850-2862 Crossref PubMed Scopus (91) Google Scholar , 19 Lippé S. Bulteau C. Dorfmuller G. Audren F. Delalande O. Jambaqué I. Cognitive outcome of parietooccipital resection in children with epilepsy. Epilepsia. 2010; 51: 2047-2057 Crossref PubMed Scopus (21) Google Scholar , 20 Chieffo D. Lettori D. Contaldo I. et al. Surgery of children with frontal lobe lesional epilepsy: neuropsychological study. Brain Dev. 2011; 33: 310-315 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar ]. On the other hand, behavioral and social improvement after successful surgery appears to be a more realistic goal, and normalization of quality of life is possible [ [21] Mikati M. Rahi A. Shamseddine A. Mroueh S. Shoeib H. Comair Y. Marked benefits in physical activity and well-being, but not in functioning domains, 2 years after successful epilepsy surgery in children. Epilepsy Behav. 2008; 12: 145-149 Abstract Full Text Full Text PDF PubMed Scopus (29) Google Scholar ]. However, inconsistencies and controversial results concern the behavioral and psychosocial outcomes of pediatric epilepsy surgery and the high rates of psychiatric diagnoses in children coming to epilepsy surgery make it unavoidable to ask the question: How much of an impact is successful resective surgery likely to have?" @default.
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- W2034341369 date "2011-12-01" @default.
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- W2034341369 title "Internalizing disorders and psychosocial functioning in the context of successful epilepsy surgery in children: Implications for a comprehensive approach and a global perspective of treatment" @default.
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