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- W2034346022 abstract "Real-time analyses have revealed that some newly synthesized neurofilament (NF) subunits translocate into and along axonal neurites by moving along the inner plasma membrane surface, suggesting that they may translocate against the submembrane actin cortex. We therefore examined whether or not NF axonal transport was dependent on actin and myosin. Perturbation of filamentous actin in NB2a/d1 cells with cytochalasin B inhibited translocation of subunits into axonal neurites and inhibited bidirectional translocation of NF subunits within neurites. Intravitreal injection of cytochalasin B inhibited NF axonal transport in optic axons in a dose-response manner. NF subunits were coprecipitated from NB2a/d1 cells by an anti-myosin antibody, and myosin colocalized with NFs in immunofluorescent analyses. The myosin light chain kinase inhibitor ML-7 and the myosin ATPase inhibitor 2,3-butanedione-2-monoxime perturbed NF translocation within NB2a/d1 axonal neurites. These findings suggest that some NF subunits may undergo axonal transport via myosin-mediated interactions with the actin cortex." @default.
- W2034346022 created "2016-06-24" @default.
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- W2034346022 date "2004-10-27" @default.
- W2034346022 modified "2023-10-11" @default.
- W2034346022 title "Neurofilament Transport Is Dependent on Actin and Myosin" @default.
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- W2034346022 cites W2170671667 @default.
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- W2034346022 doi "https://doi.org/10.1523/jneurosci.1665-04.2004" @default.
- W2034346022 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6730143" @default.
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