Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034353491> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2034353491 endingPage "73" @default.
- W2034353491 startingPage "63" @default.
- W2034353491 abstract "In the 1950s the use of primary rhesus macaque kidney cultures to propagate poliovirus for vaccine production led to the contamination of vaccines with simian virus 40 (SV40). African green monkey kidney (AGMK) cultures free of SV40 were used as an alternative cell substrate for vaccine manufacture. In this study we evaluate oral poliovirus seeds, vaccine bulks and vaccines themselves for the presence of a common contaminant of AGMK cultures, simian cytomegalovirus (SCMV). Using sensitive polymerase chain reaction (PCR) techniques, nearly half of the samples analysed were found to be contaminated with SCMV sequences. However, vaccine bulks, positive by PCR for SCMV failed to show any evidence of infectious virus in these studies. One poliovirus vaccine and one seed, propagated on rhesus macaque kidney cultures were found to be positive for the rhesus monkey CMV by PCR." @default.
- W2034353491 created "2016-06-24" @default.
- W2034353491 creator A5041454171 @default.
- W2034353491 creator A5065119343 @default.
- W2034353491 creator A5066842721 @default.
- W2034353491 creator A5071139482 @default.
- W2034353491 creator A5073269960 @default.
- W2034353491 date "2003-03-01" @default.
- W2034353491 modified "2023-10-16" @default.
- W2034353491 title "Simian cytomegalovirus and contamination of oral poliovirus vaccines" @default.
- W2034353491 cites W1486985012 @default.
- W2034353491 cites W1522893804 @default.
- W2034353491 cites W1532627765 @default.
- W2034353491 cites W1581155766 @default.
- W2034353491 cites W1885161560 @default.
- W2034353491 cites W1912151827 @default.
- W2034353491 cites W1993874880 @default.
- W2034353491 cites W1999192143 @default.
- W2034353491 cites W2018694254 @default.
- W2034353491 cites W2057170678 @default.
- W2034353491 cites W2106882534 @default.
- W2034353491 cites W2121501983 @default.
- W2034353491 cites W2153827214 @default.
- W2034353491 cites W2316784411 @default.
- W2034353491 cites W4298063918 @default.
- W2034353491 doi "https://doi.org/10.1016/s1045-1056(02)00094-5" @default.
- W2034353491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12623061" @default.
- W2034353491 hasPublicationYear "2003" @default.
- W2034353491 type Work @default.
- W2034353491 sameAs 2034353491 @default.
- W2034353491 citedByCount "14" @default.
- W2034353491 countsByYear W20343534912012 @default.
- W2034353491 countsByYear W20343534912014 @default.
- W2034353491 countsByYear W20343534912015 @default.
- W2034353491 countsByYear W20343534912018 @default.
- W2034353491 countsByYear W20343534912019 @default.
- W2034353491 countsByYear W20343534912022 @default.
- W2034353491 countsByYear W20343534912023 @default.
- W2034353491 crossrefType "journal-article" @default.
- W2034353491 hasAuthorship W2034353491A5041454171 @default.
- W2034353491 hasAuthorship W2034353491A5065119343 @default.
- W2034353491 hasAuthorship W2034353491A5066842721 @default.
- W2034353491 hasAuthorship W2034353491A5071139482 @default.
- W2034353491 hasAuthorship W2034353491A5073269960 @default.
- W2034353491 hasConcept C104317684 @default.
- W2034353491 hasConcept C151730666 @default.
- W2034353491 hasConcept C159047783 @default.
- W2034353491 hasConcept C2522874641 @default.
- W2034353491 hasConcept C2776409557 @default.
- W2034353491 hasConcept C2776488936 @default.
- W2034353491 hasConcept C2777732132 @default.
- W2034353491 hasConcept C2778950215 @default.
- W2034353491 hasConcept C2779175743 @default.
- W2034353491 hasConcept C2779631682 @default.
- W2034353491 hasConcept C2780727368 @default.
- W2034353491 hasConcept C2910145492 @default.
- W2034353491 hasConcept C49105822 @default.
- W2034353491 hasConcept C54355233 @default.
- W2034353491 hasConcept C86803240 @default.
- W2034353491 hasConcept C89423630 @default.
- W2034353491 hasConceptScore W2034353491C104317684 @default.
- W2034353491 hasConceptScore W2034353491C151730666 @default.
- W2034353491 hasConceptScore W2034353491C159047783 @default.
- W2034353491 hasConceptScore W2034353491C2522874641 @default.
- W2034353491 hasConceptScore W2034353491C2776409557 @default.
- W2034353491 hasConceptScore W2034353491C2776488936 @default.
- W2034353491 hasConceptScore W2034353491C2777732132 @default.
- W2034353491 hasConceptScore W2034353491C2778950215 @default.
- W2034353491 hasConceptScore W2034353491C2779175743 @default.
- W2034353491 hasConceptScore W2034353491C2779631682 @default.
- W2034353491 hasConceptScore W2034353491C2780727368 @default.
- W2034353491 hasConceptScore W2034353491C2910145492 @default.
- W2034353491 hasConceptScore W2034353491C49105822 @default.
- W2034353491 hasConceptScore W2034353491C54355233 @default.
- W2034353491 hasConceptScore W2034353491C86803240 @default.
- W2034353491 hasConceptScore W2034353491C89423630 @default.
- W2034353491 hasIssue "1" @default.
- W2034353491 hasLocation W20343534911 @default.
- W2034353491 hasLocation W20343534912 @default.
- W2034353491 hasOpenAccess W2034353491 @default.
- W2034353491 hasPrimaryLocation W20343534911 @default.
- W2034353491 hasRelatedWork W180428298 @default.
- W2034353491 hasRelatedWork W1969968206 @default.
- W2034353491 hasRelatedWork W2007287624 @default.
- W2034353491 hasRelatedWork W2045687854 @default.
- W2034353491 hasRelatedWork W2068354089 @default.
- W2034353491 hasRelatedWork W2070813973 @default.
- W2034353491 hasRelatedWork W2159552369 @default.
- W2034353491 hasRelatedWork W2357501381 @default.
- W2034353491 hasRelatedWork W2412402955 @default.
- W2034353491 hasRelatedWork W31547710 @default.
- W2034353491 hasVolume "31" @default.
- W2034353491 isParatext "false" @default.
- W2034353491 isRetracted "false" @default.
- W2034353491 magId "2034353491" @default.
- W2034353491 workType "article" @default.