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- W2034364957 abstract "The work of Montagna, Uno, and others1–4 using the stumptailed macaque as a nonhuman baldness model has contributed to further advancement of our understanding of hair loss by providing a model to test various therapeutic modalities; however, the small number of macaques available and the high cost of maintaining these animals unfortunately limit their use in hair research. Although mutations for hair loss occur frequently in laboratory rodents, to the best of our knowledge, androgen-mediated alopecia has never been described. This report demonstrates a mutation in our mouse colony in which the onset of alopecia is dependent upon the presence of androgens. Because alopecia in this mutation parallels that of baldness in man, we propose the use of this animal as an alternative model for studying the mechanism or mechanisms controlling the balding phenomenon and for screening of compounds that may be of therapeutic value." @default.
- W2034364957 created "2016-06-24" @default.
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- W2034364957 date "1988-10-01" @default.
- W2034364957 modified "2023-09-27" @default.
- W2034364957 title "The effect of testosterone, cyproterone acetate, and minoxidil on hair loss in the androchronogenetic alopecia mouse" @default.
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- W2034364957 doi "https://doi.org/10.1016/0738-081x(88)90083-1" @default.
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