FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034365540> ?p ?o ?g. }

• W2034365540 endingPage "2910" @default.
• W2034365540 startingPage "2907" @default.
• W2034365540 abstract "We report here a supramolecular strategy to directly assemble the small molecular hydrophobic anticancer drug camptothecin (CPT) into discrete, stable, well-defined nanostructures with a high and quantitative drug loading. Depending on the number of CPTs in the molecular design, the resulting nanostructures can be either nanofibers or nanotubes, and have a fixed CPT loading content ranging from 23% to 38%. We found that formation of nanostructures provides protection for both the CPT drug and the biodegradable linker from the external environment and thus offers a mechanism for controlled release of CPT. Under tumor-relevant conditions, these drug nanostructures can release the bioactive form of CPT and show in vitro efficacy against a number of cancer cell lines. This strategy can be extended to construct nanostructures of other types of anticancer drugs and thus presents new opportunities for the development of self-delivering drugs for cancer therapeutics." @default.
• W2034365540 created "2016-06-24" @default.
• W2034365540 creator A5048005939 @default.
• W2034365540 creator A5068842667 @default.
• W2034365540 creator A5077586136 @default.
• W2034365540 creator A5080755349 @default.
• W2034365540 creator A5085166899 @default.
• W2034365540 date "2013-02-13" @default.
• W2034365540 modified "2023-10-11" @default.
• W2034365540 title "Supramolecular Nanostructures Formed by Anticancer Drug Assembly" @default.
• W2034365540 cites W1966328890 @default.
• W2034365540 cites W1967988795 @default.
• W2034365540 cites W1970544135 @default.
• W2034365540 cites W1975828910 @default.
• W2034365540 cites W1986802370 @default.
• W2034365540 cites W1992215904 @default.
• W2034365540 cites W1994486848 @default.
• W2034365540 cites W2006532602 @default.
• W2034365540 cites W2009633522 @default.
• W2034365540 cites W2013298034 @default.
• W2034365540 cites W2016097990 @default.
• W2034365540 cites W2023096851 @default.
• W2034365540 cites W2024787650 @default.
• W2034365540 cites W2026571103 @default.
• W2034365540 cites W2032760352 @default.
• W2034365540 cites W2057839591 @default.
• W2034365540 cites W2061510929 @default.
• W2034365540 cites W2066315608 @default.
• W2034365540 cites W2070534090 @default.
• W2034365540 cites W2071636590 @default.
• W2034365540 cites W2087094217 @default.
• W2034365540 cites W2096503214 @default.
• W2034365540 cites W2104558356 @default.
• W2034365540 cites W2114343111 @default.
• W2034365540 cites W2129659516 @default.
• W2034365540 cites W2140898147 @default.
• W2034365540 cites W2145479354 @default.
• W2034365540 cites W2146274229 @default.
• W2034365540 cites W2146639342 @default.
• W2034365540 cites W2165535625 @default.
• W2034365540 cites W2166967403 @default.
• W2034365540 cites W2167947388 @default.
• W2034365540 cites W2316816338 @default.
• W2034365540 cites W3023255929 @default.
• W2034365540 cites W4212814362 @default.
• W2034365540 doi "https://doi.org/10.1021/ja3115983" @default.
• W2034365540 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3609949" @default.
• W2034365540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23379791" @default.
• W2034365540 hasPublicationYear "2013" @default.
• W2034365540 type Work @default.
• W2034365540 sameAs 2034365540 @default.
• W2034365540 citedByCount "459" @default.
• W2034365540 countsByYear W20343655402013 @default.
• W2034365540 countsByYear W20343655402014 @default.
• W2034365540 countsByYear W20343655402015 @default.
• W2034365540 countsByYear W20343655402016 @default.
• W2034365540 countsByYear W20343655402017 @default.
• W2034365540 countsByYear W20343655402018 @default.
• W2034365540 countsByYear W20343655402019 @default.
• W2034365540 countsByYear W20343655402020 @default.
• W2034365540 countsByYear W20343655402021 @default.
• W2034365540 countsByYear W20343655402022 @default.
• W2034365540 countsByYear W20343655402023 @default.
• W2034365540 crossrefType "journal-article" @default.
• W2034365540 hasAuthorship W2034365540A5048005939 @default.
• W2034365540 hasAuthorship W2034365540A5068842667 @default.
• W2034365540 hasAuthorship W2034365540A5077586136 @default.
• W2034365540 hasAuthorship W2034365540A5080755349 @default.
• W2034365540 hasAuthorship W2034365540A5085166899 @default.
• W2034365540 hasBestOaLocation W20343655402 @default.
• W2034365540 hasConcept C111919701 @default.
• W2034365540 hasConcept C171250308 @default.
• W2034365540 hasConcept C178790620 @default.
• W2034365540 hasConcept C185592680 @default.
• W2034365540 hasConcept C186187911 @default.
• W2034365540 hasConcept C192562407 @default.
• W2034365540 hasConcept C21951064 @default.
• W2034365540 hasConcept C2779682216 @default.
• W2034365540 hasConcept C2780035454 @default.
• W2034365540 hasConcept C2780557392 @default.
• W2034365540 hasConcept C3018146709 @default.
• W2034365540 hasConcept C32909587 @default.
• W2034365540 hasConcept C41008148 @default.
• W2034365540 hasConcept C55493867 @default.
• W2034365540 hasConcept C71924100 @default.
• W2034365540 hasConcept C91129048 @default.
• W2034365540 hasConcept C93275456 @default.
• W2034365540 hasConcept C98274493 @default.
• W2034365540 hasConceptScore W2034365540C111919701 @default.
• W2034365540 hasConceptScore W2034365540C171250308 @default.
• W2034365540 hasConceptScore W2034365540C178790620 @default.
• W2034365540 hasConceptScore W2034365540C185592680 @default.
• W2034365540 hasConceptScore W2034365540C186187911 @default.
• W2034365540 hasConceptScore W2034365540C192562407 @default.
• W2034365540 hasConceptScore W2034365540C21951064 @default.
• W2034365540 hasConceptScore W2034365540C2779682216 @default.
• W2034365540 hasConceptScore W2034365540C2780035454 @default.
• W2034365540 hasConceptScore W2034365540C2780557392 @default.

• next