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• W2034366704 abstract "Sixteen patients with colorectal cancer were administered 37–74 MBq (1 mg) of radioiodinated B72.3 monoclonal antibody. Pharmacokinetic analysis was carried out on plasma and urine samples. Elimination from the plasma was biexponential with a mean Tsol12α of 3.7 h and Tsol12 β of 62.4 h. The plasma clearance was fit to a two-compartment model. This was combined with a previously reported model for radioiodine to construct a composite model. There was a good correlation ( r = 0.952) between the model-predicted and observed excretion of radioiodine suggesting that the composite model is compatible with the pharmacokinetics of the radiolabelled antibody." @default.
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• W2034366704 date "1993-01-01" @default.
• W2034366704 modified "2023-10-14" @default.
• W2034366704 title "Compartmental analysis of the pharmacokinetics of radioiodinated monoclonal antibody B72.3 in colon cancer patients" @default.
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• W2034366704 doi "https://doi.org/10.1016/0969-8051(93)90136-i" @default.
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