FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034366921> ?p ?o ?g. }

• W2034366921 endingPage "306" @default.
• W2034366921 startingPage "295" @default.
• W2034366921 abstract "During the course of bovine brucellosis, Brucella abortus adheres to and infects cells of the mononuclear phagocyte system. Potential mechanisms of binding, as measured by numbers of phagocytosed bacteria, were studied in two populations of cattle genetically resistant (R) or susceptible (S) to infection with B. abortus. Live B. abortus gained entry into cultured bovine macrophages without organism-specific opsonization. Bacterial entry into macrophages from R was inhibited by the peptide RGDS, outer membrane-peptidoglycan complex from B. abortus strain RB51, anti-LFA-1 monoclonal antibody, anti-C3 antiserum, fibronectin, purified O-antigen from B. abortus lipopolysaccharide, mannan and heat-aggregated IgG. Bacterial entry into macrophages from S was inhibited by outer membrane-peptidoglycan complex, anti-LFA-1 monoclonal antibody, O-antigen and heat-aggregated IgG. The peptide RGES did not inhibit entry into macrophages from R or S. These data support the existence of organism-related receptors on monocyte-derived macrophages for B. abortus which mediate binding in the absence of serum. Secondly, there are demonstrable differences in mechanisms of binding of B. abortus to cells from cattle genetically resistant or susceptible to infection by this organism. These findings further substantiate the importance of phagocytosis and clearance functions of the mononuclear phagocyte system in resistance to bovine brucellosis. Perpetuation of infection in susceptible cattle may occur by establishing an intracellular reservoir of viable organisms. Further studies are necessary to investigate receptor affinities, and the potential for an alternate receptor for this organism in S cattle." @default.
• W2034366921 created "2016-06-24" @default.
• W2034366921 creator A5028664194 @default.
• W2034366921 creator A5062066231 @default.
• W2034366921 creator A5078349282 @default.
• W2034366921 date "1994-06-01" @default.
• W2034366921 modified "2023-10-10" @default.
• W2034366921 title "Mechanisms of binding of Brucella abortus to mononuclear phagocytes from cows naturally resistant or susceptible to brucellosis" @default.
• W2034366921 cites W1550039558 @default.
• W2034366921 cites W1884045055 @default.
• W2034366921 cites W1899633770 @default.
• W2034366921 cites W1945507732 @default.
• W2034366921 cites W1954178280 @default.
• W2034366921 cites W1963722963 @default.
• W2034366921 cites W1964338518 @default.
• W2034366921 cites W1966286149 @default.
• W2034366921 cites W1969540615 @default.
• W2034366921 cites W1982054796 @default.
• W2034366921 cites W2002204241 @default.
• W2034366921 cites W2012304750 @default.
• W2034366921 cites W2020866631 @default.
• W2034366921 cites W2027906430 @default.
• W2034366921 cites W2029157767 @default.
• W2034366921 cites W2039148627 @default.
• W2034366921 cites W2055593659 @default.
• W2034366921 cites W2061188810 @default.
• W2034366921 cites W2064626913 @default.
• W2034366921 cites W2071320646 @default.
• W2034366921 cites W2085061749 @default.
• W2034366921 cites W2085356668 @default.
• W2034366921 cites W2091535618 @default.
• W2034366921 cites W2115937925 @default.
• W2034366921 cites W2125488104 @default.
• W2034366921 cites W2129916638 @default.
• W2034366921 cites W2144011676 @default.
• W2034366921 cites W2147616933 @default.
• W2034366921 cites W2149746282 @default.
• W2034366921 cites W2165393039 @default.
• W2034366921 cites W2166924384 @default.
• W2034366921 cites W2170391371 @default.
• W2034366921 cites W82146660 @default.
• W2034366921 doi "https://doi.org/10.1016/0165-2427(94)90103-1" @default.
• W2034366921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7941309" @default.
• W2034366921 hasPublicationYear "1994" @default.
• W2034366921 type Work @default.
• W2034366921 sameAs 2034366921 @default.
• W2034366921 citedByCount "55" @default.
• W2034366921 countsByYear W20343669212012 @default.
• W2034366921 countsByYear W20343669212013 @default.
• W2034366921 countsByYear W20343669212014 @default.
• W2034366921 countsByYear W20343669212015 @default.
• W2034366921 countsByYear W20343669212016 @default.
• W2034366921 countsByYear W20343669212018 @default.
• W2034366921 countsByYear W20343669212019 @default.
• W2034366921 countsByYear W20343669212020 @default.
• W2034366921 countsByYear W20343669212021 @default.
• W2034366921 crossrefType "journal-article" @default.
• W2034366921 hasAuthorship W2034366921A5028664194 @default.
• W2034366921 hasAuthorship W2034366921A5062066231 @default.
• W2034366921 hasAuthorship W2034366921A5078349282 @default.
• W2034366921 hasConcept C147483822 @default.
• W2034366921 hasConcept C159047783 @default.
• W2034366921 hasConcept C159654299 @default.
• W2034366921 hasConcept C160448771 @default.
• W2034366921 hasConcept C168507396 @default.
• W2034366921 hasConcept C19702531 @default.
• W2034366921 hasConcept C202751555 @default.
• W2034366921 hasConcept C203014093 @default.
• W2034366921 hasConcept C2776634448 @default.
• W2034366921 hasConcept C2777692091 @default.
• W2034366921 hasConcept C2777700362 @default.
• W2034366921 hasConcept C2778754761 @default.
• W2034366921 hasConcept C2779244956 @default.
• W2034366921 hasConcept C2780767784 @default.
• W2034366921 hasConcept C2781028839 @default.
• W2034366921 hasConcept C2781429187 @default.
• W2034366921 hasConcept C523546767 @default.
• W2034366921 hasConcept C542903549 @default.
• W2034366921 hasConcept C54355233 @default.
• W2034366921 hasConcept C55493867 @default.
• W2034366921 hasConcept C86803240 @default.
• W2034366921 hasConcept C89372155 @default.
• W2034366921 hasConcept C89423630 @default.
• W2034366921 hasConcept C91523082 @default.
• W2034366921 hasConceptScore W2034366921C147483822 @default.
• W2034366921 hasConceptScore W2034366921C159047783 @default.
• W2034366921 hasConceptScore W2034366921C159654299 @default.
• W2034366921 hasConceptScore W2034366921C160448771 @default.
• W2034366921 hasConceptScore W2034366921C168507396 @default.
• W2034366921 hasConceptScore W2034366921C19702531 @default.
• W2034366921 hasConceptScore W2034366921C202751555 @default.
• W2034366921 hasConceptScore W2034366921C203014093 @default.
• W2034366921 hasConceptScore W2034366921C2776634448 @default.
• W2034366921 hasConceptScore W2034366921C2777692091 @default.
• W2034366921 hasConceptScore W2034366921C2777700362 @default.
• W2034366921 hasConceptScore W2034366921C2778754761 @default.
• W2034366921 hasConceptScore W2034366921C2779244956 @default.
• W2034366921 hasConceptScore W2034366921C2780767784 @default.

• next