Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034368390> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2034368390 endingPage "55" @default.
- W2034368390 startingPage "47" @default.
- W2034368390 abstract "It is an intriguing question whether the proteins and enzymes could harbor the unnatural amino acid analogues and retain their activity. The present report reviews the published data on the enzymes harboring unnatural amino acids and presents the experimental results demonstrating the phenomenon of the cells' normal growth even if a substantial part of one amino acid is substituted by its element-organic analogue. Alkaline phosphatase, aspartate transcarbamylase, β-lactamase, T4 lisozyme and glutathione transferase containing various unnatural amino acids are reviewed in this report. The yeast cell growth in the presence of 4-fluorophenylalanine (FPA), being the element-organic unnatural amino acid, has been studied and the analogue content in the total cell protein determined. A significant part (35–40%) of phenylalanine was found to be replaced by FPA and the cells continued to function normally. FPA-resistant phenotype capable of growing in FPA presence has also been selected. The FPA content in the protein of the resistant strain has also been determined and it was found that 30–40% of phenylalanine was replaced by FPA." @default.
- W2034368390 created "2016-06-24" @default.
- W2034368390 creator A5016960616 @default.
- W2034368390 creator A5066749412 @default.
- W2034368390 creator A5069866480 @default.
- W2034368390 date "2000-10-01" @default.
- W2034368390 modified "2023-10-17" @default.
- W2034368390 title "Unnatural amino acids in enzymes and proteins" @default.
- W2034368390 cites W133784169 @default.
- W2034368390 cites W1491737408 @default.
- W2034368390 cites W1507111189 @default.
- W2034368390 cites W1536531155 @default.
- W2034368390 cites W1538256573 @default.
- W2034368390 cites W1563319163 @default.
- W2034368390 cites W1580044524 @default.
- W2034368390 cites W1594159256 @default.
- W2034368390 cites W187096958 @default.
- W2034368390 cites W1969303801 @default.
- W2034368390 cites W1988858733 @default.
- W2034368390 cites W1999654411 @default.
- W2034368390 cites W2001210310 @default.
- W2034368390 cites W2009313044 @default.
- W2034368390 cites W2012200664 @default.
- W2034368390 cites W2017007736 @default.
- W2034368390 cites W2019451913 @default.
- W2034368390 cites W2022781009 @default.
- W2034368390 cites W2024741001 @default.
- W2034368390 cites W2026130809 @default.
- W2034368390 cites W2028384041 @default.
- W2034368390 cites W2039586371 @default.
- W2034368390 cites W2051138881 @default.
- W2034368390 cites W2057957385 @default.
- W2034368390 cites W2062518754 @default.
- W2034368390 cites W2067013502 @default.
- W2034368390 cites W2134418875 @default.
- W2034368390 cites W2156377423 @default.
- W2034368390 cites W3154515224 @default.
- W2034368390 cites W4250740720 @default.
- W2034368390 doi "https://doi.org/10.1016/s1381-1177(00)00107-7" @default.
- W2034368390 hasPublicationYear "2000" @default.
- W2034368390 type Work @default.
- W2034368390 sameAs 2034368390 @default.
- W2034368390 citedByCount "11" @default.
- W2034368390 crossrefType "journal-article" @default.
- W2034368390 hasAuthorship W2034368390A5016960616 @default.
- W2034368390 hasAuthorship W2034368390A5066749412 @default.
- W2034368390 hasAuthorship W2034368390A5069866480 @default.
- W2034368390 hasConcept C160160445 @default.
- W2034368390 hasConcept C181199279 @default.
- W2034368390 hasConcept C185592680 @default.
- W2034368390 hasConcept C2777431362 @default.
- W2034368390 hasConcept C2779222958 @default.
- W2034368390 hasConcept C515207424 @default.
- W2034368390 hasConcept C55493867 @default.
- W2034368390 hasConcept C86803240 @default.
- W2034368390 hasConceptScore W2034368390C160160445 @default.
- W2034368390 hasConceptScore W2034368390C181199279 @default.
- W2034368390 hasConceptScore W2034368390C185592680 @default.
- W2034368390 hasConceptScore W2034368390C2777431362 @default.
- W2034368390 hasConceptScore W2034368390C2779222958 @default.
- W2034368390 hasConceptScore W2034368390C515207424 @default.
- W2034368390 hasConceptScore W2034368390C55493867 @default.
- W2034368390 hasConceptScore W2034368390C86803240 @default.
- W2034368390 hasIssue "1-3" @default.
- W2034368390 hasLocation W20343683901 @default.
- W2034368390 hasOpenAccess W2034368390 @default.
- W2034368390 hasPrimaryLocation W20343683901 @default.
- W2034368390 hasRelatedWork W1644178486 @default.
- W2034368390 hasRelatedWork W1981027481 @default.
- W2034368390 hasRelatedWork W1981229103 @default.
- W2034368390 hasRelatedWork W1999370887 @default.
- W2034368390 hasRelatedWork W2008530076 @default.
- W2034368390 hasRelatedWork W2018021476 @default.
- W2034368390 hasRelatedWork W2060862331 @default.
- W2034368390 hasRelatedWork W2083199418 @default.
- W2034368390 hasRelatedWork W2132770903 @default.
- W2034368390 hasRelatedWork W2137957492 @default.
- W2034368390 hasVolume "10" @default.
- W2034368390 isParatext "false" @default.
- W2034368390 isRetracted "false" @default.
- W2034368390 magId "2034368390" @default.
- W2034368390 workType "article" @default.