FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034371514> ?p ?o ?g. }

• W2034371514 endingPage "50" @default.
• W2034371514 startingPage "42" @default.
• W2034371514 abstract "Ca2+-dependent regulation of the ion current through the alpha1Cbeta2aalpha2delta-1 (L-type) calcium channel transiently expressed in HEK 293 cells was investigated using whole cell patch clamp method. Ca2+ or Na+ ions were used as a charge carrier. Intracellular Ca2+ was either buffered by 10 mM EGTA or 200 microM Ca2+ was added into non-buffered intracellular solution. Free intracellular Ca2+ inactivated permanently about 80% of the L-type calcium current. The L-type calcium channel inactivated during a depolarizing pulse with two time constants, tau(fast) and tau(slow). Free intracellular calcium accelerated both time constants. Effect on the tau(slow) was more pronounced. About 80% of the channel inactivation during brief depolarizing pulse could be attributed to a Ca2+-dependent mechanism and 20% to a voltage-dependent mechanism. When Na+ ions were used as a charge carrier, the L-type current still inactivated with two time constants that were 10 times slower and were virtually voltage-independent. Ca2+ ions stabilized the inactivated state of the channel in a concentration-dependent manner." @default.
• W2034371514 created "2016-06-24" @default.
• W2034371514 creator A5016660545 @default.
• W2034371514 creator A5091874127 @default.
• W2034371514 date "2005-05-01" @default.
• W2034371514 modified "2023-10-14" @default.
• W2034371514 title "Ca2+- and voltage-dependent inactivation of the expressed L-type Cav1.2 calcium channel" @default.
• W2034371514 cites W1549372325 @default.
• W2034371514 cites W154975620 @default.
• W2034371514 cites W1628979938 @default.
• W2034371514 cites W1963552271 @default.
• W2034371514 cites W1965163623 @default.
• W2034371514 cites W1979624945 @default.
• W2034371514 cites W1984694963 @default.
• W2034371514 cites W1989248258 @default.
• W2034371514 cites W1992469716 @default.
• W2034371514 cites W1995252393 @default.
• W2034371514 cites W2008864455 @default.
• W2034371514 cites W2009613933 @default.
• W2034371514 cites W2012691619 @default.
• W2034371514 cites W2033155582 @default.
• W2034371514 cites W2043309628 @default.
• W2034371514 cites W2055984902 @default.
• W2034371514 cites W2069905444 @default.
• W2034371514 cites W2072926617 @default.
• W2034371514 cites W2073758404 @default.
• W2034371514 cites W2078798679 @default.
• W2034371514 cites W2093450222 @default.
• W2034371514 cites W209805056 @default.
• W2034371514 cites W2121559062 @default.
• W2034371514 cites W2132447765 @default.
• W2034371514 cites W2140321883 @default.
• W2034371514 cites W2141479114 @default.
• W2034371514 cites W2146411874 @default.
• W2034371514 cites W2167319899 @default.
• W2034371514 cites W2170164022 @default.
• W2034371514 cites W2243608582 @default.
• W2034371514 cites W2314318656 @default.
• W2034371514 cites W2420864363 @default.
• W2034371514 doi "https://doi.org/10.1016/j.abb.2005.02.025" @default.
• W2034371514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15820215" @default.
• W2034371514 hasPublicationYear "2005" @default.
• W2034371514 type Work @default.
• W2034371514 sameAs 2034371514 @default.
• W2034371514 citedByCount "23" @default.
• W2034371514 countsByYear W20343715142012 @default.
• W2034371514 countsByYear W20343715142013 @default.
• W2034371514 countsByYear W20343715142014 @default.
• W2034371514 countsByYear W20343715142015 @default.
• W2034371514 countsByYear W20343715142017 @default.
• W2034371514 countsByYear W20343715142018 @default.
• W2034371514 countsByYear W20343715142020 @default.
• W2034371514 countsByYear W20343715142021 @default.
• W2034371514 countsByYear W20343715142022 @default.
• W2034371514 countsByYear W20343715142023 @default.
• W2034371514 crossrefType "journal-article" @default.
• W2034371514 hasAuthorship W2034371514A5016660545 @default.
• W2034371514 hasAuthorship W2034371514A5091874127 @default.
• W2034371514 hasConcept C113196181 @default.
• W2034371514 hasConcept C119599485 @default.
• W2034371514 hasConcept C121332964 @default.
• W2034371514 hasConcept C12554922 @default.
• W2034371514 hasConcept C127413603 @default.
• W2034371514 hasConcept C147944092 @default.
• W2034371514 hasConcept C165801399 @default.
• W2034371514 hasConcept C170493617 @default.
• W2034371514 hasConcept C178790620 @default.
• W2034371514 hasConcept C185592680 @default.
• W2034371514 hasConcept C18699975 @default.
• W2034371514 hasConcept C2777658833 @default.
• W2034371514 hasConcept C2780167933 @default.
• W2034371514 hasConcept C4141045 @default.
• W2034371514 hasConcept C43617362 @default.
• W2034371514 hasConcept C519063684 @default.
• W2034371514 hasConcept C55493867 @default.
• W2034371514 hasConcept C62520636 @default.
• W2034371514 hasConcept C79879829 @default.
• W2034371514 hasConcept C81370116 @default.
• W2034371514 hasConcept C85520022 @default.
• W2034371514 hasConcept C86803240 @default.
• W2034371514 hasConceptScore W2034371514C113196181 @default.
• W2034371514 hasConceptScore W2034371514C119599485 @default.
• W2034371514 hasConceptScore W2034371514C121332964 @default.
• W2034371514 hasConceptScore W2034371514C12554922 @default.
• W2034371514 hasConceptScore W2034371514C127413603 @default.
• W2034371514 hasConceptScore W2034371514C147944092 @default.
• W2034371514 hasConceptScore W2034371514C165801399 @default.
• W2034371514 hasConceptScore W2034371514C170493617 @default.
• W2034371514 hasConceptScore W2034371514C178790620 @default.
• W2034371514 hasConceptScore W2034371514C185592680 @default.
• W2034371514 hasConceptScore W2034371514C18699975 @default.
• W2034371514 hasConceptScore W2034371514C2777658833 @default.
• W2034371514 hasConceptScore W2034371514C2780167933 @default.
• W2034371514 hasConceptScore W2034371514C4141045 @default.
• W2034371514 hasConceptScore W2034371514C43617362 @default.
• W2034371514 hasConceptScore W2034371514C519063684 @default.
• W2034371514 hasConceptScore W2034371514C55493867 @default.
• W2034371514 hasConceptScore W2034371514C62520636 @default.

• next