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• W2034371575 abstract "We analyzed the periodic patterns in E. coli promoters and compared the distributions of the corresponding patterns in promoters and in the complete genome to elucidate their function. Except the three-base periodicity, coincident with that in the coding regions and growing stronger in the region downstream from the transcriptions start (TS), all other salient periodicities are peaked upstream of TS. We found that helical periodicities with the lengths about B-helix pitch ~10.2-10.5 bp and A-helix pitch ~10.8-11.1 bp coexist in the genomic sequences. We mapped the distributions of stretches with A-, B-, and Z-like DNA periodicities onto E. coli genome. All three periodicities tend to concentrate within non-coding regions when their intensity becomes stronger and prevail in the promoter sequences. The comparison with available experimental data indicates that promoters with the most pronounced periodicities may be related to the supercoiling-sensitive genes." @default.
• W2034371575 created "2016-06-24" @default.
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• W2034371575 date "2011-09-01" @default.
• W2034371575 modified "2023-10-16" @default.
• W2034371575 title "Coexistence of different base periodicities in prokaryotic genomes as related to DNA curvature, supercoiling, and transcription" @default.
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• W2034371575 doi "https://doi.org/10.1016/j.ygeno.2011.06.006" @default.
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