FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034371587> ?p ?o ?g. }

• W2034371587 endingPage "550" @default.
• W2034371587 startingPage "543" @default.
• W2034371587 abstract "Afferent information from the heart and the lung is conveyed to the brainstem by primary afferent fibers originating from vagal sensory neurons (jugular–nodose ganglion complex, JNC). The present study was made to evaluate if release of the sensory neuropeptide calcitonin gene-related peptide (CGRP) from the JNC can be used as a model for future studies on changes in neuropeptide release under pathological conditions of the heart. Freshly isolated rat JNC’s were passed through a series of solutions based on oxygenated synthetic interstitial fluid (SIF). Substances such as the TRPV1 receptor agonist capsaicin and the nitric oxide (NO) donor sodium nitroprusside (SNP) were added as excitatory test stimuli. The eluates were processed using an enzyme immuno-assay (EIA) for measurement of CGRP concentrations. Immunohistochemistry was used to visualize CGRP containing and NO producing neurons in the JNC. Both SNP and capsaicin caused significant increases in CGRP release. CGRP-immunoreactive neurons (somata) were preferentially found in the jugular ganglion, whereas neurons immunoreactive for neuronal NO synthase were mostly localized in the nodose ganglion. The present study demonstrates an easily reproducible model for measuring stimulated CGRP release from vagal afferents arising from the JNC. Nitric oxide produced by vagal afferents may stimulate CGRP release upon afferent activation." @default.
• W2034371587 created "2016-06-24" @default.
• W2034371587 creator A5018505044 @default.
• W2034371587 creator A5026365585 @default.
• W2034371587 creator A5028720758 @default.
• W2034371587 creator A5044049622 @default.
• W2034371587 creator A5053298548 @default.
• W2034371587 creator A5091196503 @default.
• W2034371587 date "2008-10-01" @default.
• W2034371587 modified "2023-09-30" @default.
• W2034371587 title "Release of calcitonin gene-related peptide from the jugular–nodose ganglion complex in rats – A new model to examine the role of cardiac peptidergic and nitrergic innervation" @default.
• W2034371587 cites W1494105143 @default.
• W2034371587 cites W1968206565 @default.
• W2034371587 cites W1972382519 @default.
• W2034371587 cites W1976652525 @default.
• W2034371587 cites W1977213715 @default.
• W2034371587 cites W1977326055 @default.
• W2034371587 cites W1977931776 @default.
• W2034371587 cites W1985500757 @default.
• W2034371587 cites W2008774157 @default.
• W2034371587 cites W2010784234 @default.
• W2034371587 cites W2010835114 @default.
• W2034371587 cites W2010860671 @default.
• W2034371587 cites W2013339589 @default.
• W2034371587 cites W2020578293 @default.
• W2034371587 cites W2028912650 @default.
• W2034371587 cites W2031081542 @default.
• W2034371587 cites W2038513066 @default.
• W2034371587 cites W2038864055 @default.
• W2034371587 cites W2042140454 @default.
• W2034371587 cites W2042638731 @default.
• W2034371587 cites W2047265728 @default.
• W2034371587 cites W2061215083 @default.
• W2034371587 cites W2061762458 @default.
• W2034371587 cites W2064501211 @default.
• W2034371587 cites W2065585464 @default.
• W2034371587 cites W2066012736 @default.
• W2034371587 cites W2070049849 @default.
• W2034371587 cites W2070906121 @default.
• W2034371587 cites W2072204309 @default.
• W2034371587 cites W2073133096 @default.
• W2034371587 cites W2075777639 @default.
• W2034371587 cites W2077693540 @default.
• W2034371587 cites W2079345841 @default.
• W2034371587 cites W2084945423 @default.
• W2034371587 cites W2085230576 @default.
• W2034371587 cites W2087904308 @default.
• W2034371587 cites W2088434753 @default.
• W2034371587 cites W2092263710 @default.
• W2034371587 cites W2094858627 @default.
• W2034371587 cites W2155781531 @default.
• W2034371587 cites W2313574624 @default.
• W2034371587 doi "https://doi.org/10.1016/j.npep.2008.08.002" @default.
• W2034371587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18809208" @default.
• W2034371587 hasPublicationYear "2008" @default.
• W2034371587 type Work @default.
• W2034371587 sameAs 2034371587 @default.
• W2034371587 citedByCount "7" @default.
• W2034371587 countsByYear W20343715872013 @default.
• W2034371587 countsByYear W20343715872014 @default.
• W2034371587 countsByYear W20343715872015 @default.
• W2034371587 countsByYear W20343715872022 @default.
• W2034371587 crossrefType "journal-article" @default.
• W2034371587 hasAuthorship W2034371587A5018505044 @default.
• W2034371587 hasAuthorship W2034371587A5026365585 @default.
• W2034371587 hasAuthorship W2034371587A5028720758 @default.
• W2034371587 hasAuthorship W2034371587A5044049622 @default.
• W2034371587 hasAuthorship W2034371587A5053298548 @default.
• W2034371587 hasAuthorship W2034371587A5091196503 @default.
• W2034371587 hasConcept C118303440 @default.
• W2034371587 hasConcept C126322002 @default.
• W2034371587 hasConcept C134018914 @default.
• W2034371587 hasConcept C155164980 @default.
• W2034371587 hasConcept C160145004 @default.
• W2034371587 hasConcept C163170386 @default.
• W2034371587 hasConcept C169760540 @default.
• W2034371587 hasConcept C170493617 @default.
• W2034371587 hasConcept C185592680 @default.
• W2034371587 hasConcept C24998067 @default.
• W2034371587 hasConcept C2779610285 @default.
• W2034371587 hasConcept C2779627488 @default.
• W2034371587 hasConcept C2780051329 @default.
• W2034371587 hasConcept C2781334511 @default.
• W2034371587 hasConcept C2781404750 @default.
• W2034371587 hasConcept C2909127448 @default.
• W2034371587 hasConcept C519581460 @default.
• W2034371587 hasConcept C71924100 @default.
• W2034371587 hasConcept C86803240 @default.
• W2034371587 hasConceptScore W2034371587C118303440 @default.
• W2034371587 hasConceptScore W2034371587C126322002 @default.
• W2034371587 hasConceptScore W2034371587C134018914 @default.
• W2034371587 hasConceptScore W2034371587C155164980 @default.
• W2034371587 hasConceptScore W2034371587C160145004 @default.
• W2034371587 hasConceptScore W2034371587C163170386 @default.
• W2034371587 hasConceptScore W2034371587C169760540 @default.
• W2034371587 hasConceptScore W2034371587C170493617 @default.
• W2034371587 hasConceptScore W2034371587C185592680 @default.
• W2034371587 hasConceptScore W2034371587C24998067 @default.

• next