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• W2034372132 abstract "Introduction: Le stade tumoral, le grade nucleaire et le type histologique sont consideres comme les facteurs pronostiques les plus importants dans le carcinome a cellules renales de sorte qu’il est devenu de plus en plus important d’obtenir les caracteristiques histopathologiques de la tumeur avant l’acte chirurgical. Objectif: L’interet de notre etude est de savoir jusqu’a quel point on peut se fier au scanner pour preciser la taille tumorale et l’interet de cette derniere pour predire les caracteristiques anatomopathologiques du cancer du rein. Patients et methodes: Nous avons realise une etude retrospective au service hospitalier d’urologie du CHU Hassan II de Fes durant la periode 2010-2012 de 35 dossiers de malades atteints du cancer du rein et ayant beneficie d’une nephrectomie totale elargie ou d’une nephrectomie partielle. Resultats: L’âge moyen de nos malades etait 56 ans avec predominance masculine (sex-ratio de 1,9/1). L’analyse anatomopathologique a montre que le carcinome a cellules claires etait le type histologique le plus frequent. La TDM a sous-estime la taille tumorale sans que ce ne soit significatif (p = 0,368). Elle avait tendance a surestimer la taille tumorale de fac¸on significative (p = 0,012) pour les tumeurs de moins de 4 cm. Dans les tumeurs de taille superieure a 4 cm, la TDM sous-estimait ou surestimait la taille tumorale sans facteur determinant et sans etre significative Notre etude a montre que tant que la taille des tumeurs augmente, il y avait une probabilite significativement plus importante que celles-ci soient des carcinomes a cellules claires (p < 0,0001). Aussi, il y avait une relation significative entre la taille tumorale et le grade nucleaire; les plus grandes tumeurs avait un grade nucleaire eleve et etaient potentiellement plus agressives. Conclusion: La presente etude reaffirme la precision de la TDM pour predire la taille des tumeurs renales mesuree a l’anatomopathologie, d’etablir le renal score afin de mieux orienter le choix therapeutique et de predire les caracteristiques anatomopathologique du carcinome a cellules renales. Mots-Cles:  cancer; rein; tomodensitometrie; anatomie pathologique; imagerie English Title:  Is there a correlation between tumor size on CT scan and pathological characteristics of kidney cancer? English Abstract Introduction: Renal cell carcinoma (RCC) may vary in prognosis according to staging, histological subtype, and Fuhrman grade. Hence, accurate evaluation of the renal masses before surgery is essential to ensure an appropriate case management. Purpose: To evaluate the value of CT-scan in providing relatively sufficient information about pathologic characteristics of a renal mass and to determine the degree of correlation between radiographic size and true gross pathologic size. Patients and methods: We retrospectively reviewed the records of 35 patients who underwent radical or partial nephrectomy for RCC at the department of urology, University Hospital Hassan II, Fez, between 2012 and 2013. Preoperative imaging was performed using CT-scan. Results: The mean patient age was 56 years with a male ascendancy, that is a sex ratio of 1.9: 1. The most common histopathological type was the clear-cell Renal Cell Carcinoma. Our study shows that in most instances, imaging by CT insignificantly underestimates true gross pathologic size of RCC (p = 0.368). For tumours less than 4 cm, the CT-scan significantly overestimate the tumor size (p = 0.012). Furthermore, for tumors greater than 4 cm, it insignificantly underestimated or overestimated the tumor size without any determining factor. In addition, as tumor size increased, there was a significant increase in the incidence of clear cell renal cell carcinoma (p < 0.0001). Large tumor size was significantly associated with histological grading and high Fuhrman grade. Conclusion: The value of CT scan as a preoperative imaging in RCC is considered to be good for predicting the size of renal tumors to establish renal score and providing pathologic characteristics to direct the planning of the surgical approach and strategy. Keywords:  cancer; kidney; computed tomography;  pathology; radiology" @default.
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• W2034372132 date "2015-03-01" @default.
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• W2034372132 title "Existe-t-il une corrélation entre la taille tumorale au scanner et les caractéristiques anatomopathologiques du cancer du rein?" @default.
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