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- W2034372903 abstract "A model-based investigation of the reactivity of a multi-phase microchannel bioreactor for the oxidation of d-sorbitol to l-sorbose by viable Gluconobacter oxydans entrapped in an adhesive, bilayer, and nano-porous latex coating has been performed. Using kinetics and mass-transfer information from literature, the overall productivity of a single microchannel was determined. For liquid and gas superficial velocities typical for monoliths and channel diameters smaller than 1000 μm, volumetric l-sorbose formation rates larger than 30 g l−1 h−1 were predicted. Since the system was approximately kinetically controlled any effort to increase the coating reactivity, for example by using thinner topcoats or improving cell viability should result in a further increase of the overall reactivity. These modeling studies should provide the basis for engineering of channel geometry, biocatalytic coating nano-porosity and thickness, coating stability, optimal reactivity and multi-phase channel flow properties for future microchannel bioreactors for high intensity microbial oxidations." @default.
- W2034372903 created "2016-06-24" @default.
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- W2034372903 date "2011-07-01" @default.
- W2034372903 modified "2023-10-18" @default.
- W2034372903 title "Engineering and modeling of thin, adhesive, microbial biocatalytic coatings for high intensity oxidations in multi-phase microchannel bioreactors" @default.
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- W2034372903 doi "https://doi.org/10.1016/j.ces.2011.02.020" @default.
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