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• W2034374445 abstract "Abstract Natural materials, such as wood and bone, possess structures fulfilling the requirements of support and transport of nutrients. Similarity in function and properties provides inspiration for investigating the possible use of wood as an implant material. Juniperus communis wood is dense, durable, and strong and has naturally impregnated essential oils that display antiseptic properties. This study investigated the toxicity of the oil, the effect of sterilization on the mechanical properties of the wood, and bone attachment with animal studies. The possible toxicity of the oil was determined orally and by intravenous injection. At low concentrations, the dose that would be released by the wood in the body could be tolerated without any detrimental effects. Sterilization of the wood in boiling water lowered the elastic modulus and modulus of rupture to a level at which the elastic modulus could be better matched to bone. Wood shaped into the form of femoral implants were implanted into rabbits and displayed good acceptance by the body up to a period of 3 years, indicating bone apposition, abutment into pores, and growth into drilled cavities. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 64A: 672–683, 2003" @default.
• W2034374445 created "2016-06-24" @default.
• W2034374445 creator A5020257155 @default.
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• W2034374445 date "2003-02-10" @default.
• W2034374445 modified "2023-10-17" @default.
• W2034374445 title "Juniper wood as a possible implant material" @default.
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• W2034374445 doi "https://doi.org/10.1002/jbm.a.10437" @default.
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