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• W2034375022 abstract "A quantitative assay involving the reaction of nitriles with glutathione and cysteine has been used as a simple in vitro screen to assess potential toxicity risk of candidate compounds in drug discovery. Studies have indicated that, when benchmarked with selected compounds, the reaction of the nitriles with glutathione can provide a useful tool for deciding whether or not to progress compounds in the absence of radiolabelling studies." @default.
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• W2034375022 date "2009-02-01" @default.
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• W2034375022 title "A simple in vitro assay for assessing the reactivity of nitrile containing compounds" @default.
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• W2034375022 doi "https://doi.org/10.1016/j.bmcl.2008.12.105" @default.
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