FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034377987> ?p ?o ?g. }

• W2034377987 endingPage "233" @default.
• W2034377987 startingPage "228" @default.
• W2034377987 abstract "A central question in the study of LTP has been to determine what role it plays in memory formation and storage. One valuable form of learning for addressing this issue is associative fear conditioning. In this paradigm an animal learns to associate a tone and shock, such that subsequent presentation of a tone evokes a fear response (freezing behavior). Recent studies indicate that overlapping cellular processes underlie fear conditioning and LTP. The fear response has generally been scored manually which is both labor-intensive and subject to potential artifacts such as inconsistent or biased results. Here we describe a simple automated method that provides unbiased and rapid analysis of animal motion. We show that measured motion, in units termed significant motion pixels (SMPs), is both linear and robust over a wide range of animal speeds and detection thresholds and scores freezing in a quantitatively similar manner to trained human observers. By comparing the frequency distribution of motion during baseline periods and to the response to fox urine (which causes unconditioned fear), we suggest that freezing and non-freezing are distinct behaviors. Finally, we show how this algorithm can be applied to a fear conditioning paradigm yielding information on long and short-term associative memory as well as habituation. This automated analysis of fear conditioning will permit a more rapid and accurate assessment of the role of LTP in memory." @default.
• W2034377987 created "2016-06-24" @default.
• W2034377987 creator A5009472826 @default.
• W2034377987 creator A5022351112 @default.
• W2034377987 creator A5024522246 @default.
• W2034377987 creator A5052872293 @default.
• W2034377987 creator A5059441599 @default.
• W2034377987 creator A5071080598 @default.
• W2034377987 date "2007-01-01" @default.
• W2034377987 modified "2023-09-27" @default.
• W2034377987 title "A robust automated method to analyze rodent motion during fear conditioning" @default.
• W2034377987 cites W1592661589 @default.
• W2034377987 cites W1967887989 @default.
• W2034377987 cites W1971433884 @default.
• W2034377987 cites W1977313055 @default.
• W2034377987 cites W2017517270 @default.
• W2034377987 cites W2019945824 @default.
• W2034377987 cites W2020199168 @default.
• W2034377987 cites W2042402461 @default.
• W2034377987 cites W2043965124 @default.
• W2034377987 cites W2068548412 @default.
• W2034377987 cites W2075665234 @default.
• W2034377987 cites W2076342064 @default.
• W2034377987 cites W2077544438 @default.
• W2034377987 cites W2122387933 @default.
• W2034377987 cites W2125252313 @default.
• W2034377987 cites W2128258712 @default.
• W2034377987 cites W2143742981 @default.
• W2034377987 cites W2148389554 @default.
• W2034377987 cites W2150244264 @default.
• W2034377987 cites W2154836288 @default.
• W2034377987 cites W2158553737 @default.
• W2034377987 cites W4250540715 @default.
• W2034377987 doi "https://doi.org/10.1016/j.neuropharm.2006.07.028" @default.
• W2034377987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16926033" @default.
• W2034377987 hasPublicationYear "2007" @default.
• W2034377987 type Work @default.
• W2034377987 sameAs 2034377987 @default.
• W2034377987 citedByCount "38" @default.
• W2034377987 countsByYear W20343779872012 @default.
• W2034377987 countsByYear W20343779872013 @default.
• W2034377987 countsByYear W20343779872014 @default.
• W2034377987 countsByYear W20343779872015 @default.
• W2034377987 countsByYear W20343779872016 @default.
• W2034377987 countsByYear W20343779872017 @default.
• W2034377987 countsByYear W20343779872018 @default.
• W2034377987 countsByYear W20343779872019 @default.
• W2034377987 countsByYear W20343779872020 @default.
• W2034377987 countsByYear W20343779872021 @default.
• W2034377987 countsByYear W20343779872022 @default.
• W2034377987 crossrefType "journal-article" @default.
• W2034377987 hasAuthorship W2034377987A5009472826 @default.
• W2034377987 hasAuthorship W2034377987A5022351112 @default.
• W2034377987 hasAuthorship W2034377987A5024522246 @default.
• W2034377987 hasAuthorship W2034377987A5052872293 @default.
• W2034377987 hasAuthorship W2034377987A5059441599 @default.
• W2034377987 hasAuthorship W2034377987A5071080598 @default.
• W2034377987 hasBestOaLocation W20343779872 @default.
• W2034377987 hasConcept C105795698 @default.
• W2034377987 hasConcept C154945302 @default.
• W2034377987 hasConcept C15744967 @default.
• W2034377987 hasConcept C159423971 @default.
• W2034377987 hasConcept C16837860 @default.
• W2034377987 hasConcept C169760540 @default.
• W2034377987 hasConcept C180747234 @default.
• W2034377987 hasConcept C202444582 @default.
• W2034377987 hasConcept C2779144063 @default.
• W2034377987 hasConcept C2781069985 @default.
• W2034377987 hasConcept C2983526489 @default.
• W2034377987 hasConcept C33923547 @default.
• W2034377987 hasConcept C39617858 @default.
• W2034377987 hasConcept C41008148 @default.
• W2034377987 hasConcept C45262634 @default.
• W2034377987 hasConcept C50610925 @default.
• W2034377987 hasConceptScore W2034377987C105795698 @default.
• W2034377987 hasConceptScore W2034377987C154945302 @default.
• W2034377987 hasConceptScore W2034377987C15744967 @default.
• W2034377987 hasConceptScore W2034377987C159423971 @default.
• W2034377987 hasConceptScore W2034377987C16837860 @default.
• W2034377987 hasConceptScore W2034377987C169760540 @default.
• W2034377987 hasConceptScore W2034377987C180747234 @default.
• W2034377987 hasConceptScore W2034377987C202444582 @default.
• W2034377987 hasConceptScore W2034377987C2779144063 @default.
• W2034377987 hasConceptScore W2034377987C2781069985 @default.
• W2034377987 hasConceptScore W2034377987C2983526489 @default.
• W2034377987 hasConceptScore W2034377987C33923547 @default.
• W2034377987 hasConceptScore W2034377987C39617858 @default.
• W2034377987 hasConceptScore W2034377987C41008148 @default.
• W2034377987 hasConceptScore W2034377987C45262634 @default.
• W2034377987 hasConceptScore W2034377987C50610925 @default.
• W2034377987 hasIssue "1" @default.
• W2034377987 hasLocation W20343779871 @default.
• W2034377987 hasLocation W20343779872 @default.
• W2034377987 hasLocation W20343779873 @default.
• W2034377987 hasOpenAccess W2034377987 @default.
• W2034377987 hasPrimaryLocation W20343779871 @default.
• W2034377987 hasRelatedWork W1981737829 @default.
• W2034377987 hasRelatedWork W2004360471 @default.

• next