Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034382620> ?p ?o ?g. }
- W2034382620 endingPage "47" @default.
- W2034382620 startingPage "37" @default.
- W2034382620 abstract "Testes from rats of different maturational ages were explored for presence of paracrine sertoli cell growth factors. Pubertal and adult testes contained a 17 kDa protein, with potent stimulatory effect on immature Sertoli cell multiplication in vitro. The bioactivity of this protein was mimicked by rat interleukin-1 (IL-1) and neutralized by IL-1 receptor antagonist. A receptor-mediated action was further supported by the demonstration of IL-1 receptor type I mRNA and protein expression in the cultured sertoli cells and in intact immature rat testes. IL-1alpha showed higher efficacy in stimulating proliferation than IL-1beta and follicle-stimulating hormone (FSH), and displayed synergistic action in combination with FSH. As IL-1alpha is constitutively produced by the rat testis and IL-1beta readily inducible by proinflammatory stimuli, our results suggest that IL-1 may serve as a growth factor for Sertoli cells under physiological and pathophysiological conditions." @default.
- W2034382620 created "2016-06-24" @default.
- W2034382620 creator A5035121631 @default.
- W2034382620 creator A5037206883 @default.
- W2034382620 creator A5046023727 @default.
- W2034382620 creator A5079465039 @default.
- W2034382620 date "2002-01-01" @default.
- W2034382620 modified "2023-10-16" @default.
- W2034382620 title "Interleukin-1 is a potent growth factor for immature rat Sertoli cells" @default.
- W2034382620 cites W1788268544 @default.
- W2034382620 cites W1933741179 @default.
- W2034382620 cites W1966983968 @default.
- W2034382620 cites W1967413976 @default.
- W2034382620 cites W1981163610 @default.
- W2034382620 cites W1986375433 @default.
- W2034382620 cites W1994130571 @default.
- W2034382620 cites W1999807078 @default.
- W2034382620 cites W2014042259 @default.
- W2034382620 cites W2020779608 @default.
- W2034382620 cites W2029651564 @default.
- W2034382620 cites W2032158597 @default.
- W2034382620 cites W2032731788 @default.
- W2034382620 cites W2034417567 @default.
- W2034382620 cites W2038123205 @default.
- W2034382620 cites W2045175993 @default.
- W2034382620 cites W2057324605 @default.
- W2034382620 cites W2059337926 @default.
- W2034382620 cites W2073686351 @default.
- W2034382620 cites W2075390316 @default.
- W2034382620 cites W2085478239 @default.
- W2034382620 cites W2089991241 @default.
- W2034382620 cites W2094451053 @default.
- W2034382620 cites W2098870010 @default.
- W2034382620 cites W2119888224 @default.
- W2034382620 cites W2122693798 @default.
- W2034382620 cites W2125499492 @default.
- W2034382620 cites W2152486718 @default.
- W2034382620 cites W2158446846 @default.
- W2034382620 cites W2161033554 @default.
- W2034382620 cites W2168632024 @default.
- W2034382620 cites W2416138507 @default.
- W2034382620 cites W4231278995 @default.
- W2034382620 cites W4231460341 @default.
- W2034382620 cites W4236011896 @default.
- W2034382620 cites W4237493180 @default.
- W2034382620 cites W4239359105 @default.
- W2034382620 cites W4240354993 @default.
- W2034382620 cites W4240978790 @default.
- W2034382620 cites W4246584799 @default.
- W2034382620 cites W4247643164 @default.
- W2034382620 cites W4293247451 @default.
- W2034382620 doi "https://doi.org/10.1016/s0303-7207(01)00680-3" @default.
- W2034382620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11850120" @default.
- W2034382620 hasPublicationYear "2002" @default.
- W2034382620 type Work @default.
- W2034382620 sameAs 2034382620 @default.
- W2034382620 citedByCount "67" @default.
- W2034382620 countsByYear W20343826202012 @default.
- W2034382620 countsByYear W20343826202013 @default.
- W2034382620 countsByYear W20343826202014 @default.
- W2034382620 countsByYear W20343826202017 @default.
- W2034382620 countsByYear W20343826202018 @default.
- W2034382620 countsByYear W20343826202019 @default.
- W2034382620 countsByYear W20343826202020 @default.
- W2034382620 countsByYear W20343826202021 @default.
- W2034382620 countsByYear W20343826202023 @default.
- W2034382620 crossrefType "journal-article" @default.
- W2034382620 hasAuthorship W2034382620A5035121631 @default.
- W2034382620 hasAuthorship W2034382620A5037206883 @default.
- W2034382620 hasAuthorship W2034382620A5046023727 @default.
- W2034382620 hasAuthorship W2034382620A5079465039 @default.
- W2034382620 hasConcept C123765429 @default.
- W2034382620 hasConcept C126322002 @default.
- W2034382620 hasConcept C134018914 @default.
- W2034382620 hasConcept C170493617 @default.
- W2034382620 hasConcept C2778575703 @default.
- W2034382620 hasConcept C2778690821 @default.
- W2034382620 hasConcept C2779279165 @default.
- W2034382620 hasConcept C2781068068 @default.
- W2034382620 hasConcept C29390026 @default.
- W2034382620 hasConcept C71315377 @default.
- W2034382620 hasConcept C71924100 @default.
- W2034382620 hasConcept C74172505 @default.
- W2034382620 hasConcept C77390185 @default.
- W2034382620 hasConcept C7876069 @default.
- W2034382620 hasConcept C86803240 @default.
- W2034382620 hasConcept C95444343 @default.
- W2034382620 hasConceptScore W2034382620C123765429 @default.
- W2034382620 hasConceptScore W2034382620C126322002 @default.
- W2034382620 hasConceptScore W2034382620C134018914 @default.
- W2034382620 hasConceptScore W2034382620C170493617 @default.
- W2034382620 hasConceptScore W2034382620C2778575703 @default.
- W2034382620 hasConceptScore W2034382620C2778690821 @default.
- W2034382620 hasConceptScore W2034382620C2779279165 @default.
- W2034382620 hasConceptScore W2034382620C2781068068 @default.
- W2034382620 hasConceptScore W2034382620C29390026 @default.
- W2034382620 hasConceptScore W2034382620C71315377 @default.
- W2034382620 hasConceptScore W2034382620C71924100 @default.