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- W2034383336 abstract "Objective To assess the effect of tranexamic acid on the quality of the surgical field. Design Prospective, randomized, double-blind study. Setting Institutional, tertiary referral hospital. Participants American Society of Anesthesiologists physical status class I patients, aged 8 to 60 months with Group II or III (Balakrishnan's classification) clefts scheduled for cleft palate repair. Interventions Children were randomized into two groups. The control group received saline, and the tranexamic acid group received tranexamic acid 10 mg/kg as a bolus, 15 minutes before incision. Main Outcome Measures Grade of surgical field on a 10-point scale, surgeon satisfaction, and primary hemorrhage. Results Significant improvements were noted in surgeon satisfaction and median grade of assessment of the surgical field (4 [interquartile range, 4 to 6] in the control group vs. 3 [interquartile range, 2 to 4] in the test group; P = .003) in the tranexamic acid group compared to the control group. Conclusion Preincision administration of 10 mg/kg of tranexamic acid significantly improved the surgical field during cleft palate repair." @default.
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- W2034383336 date "2015-09-01" @default.
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- W2034383336 title "Evaluation of the Efficacy of Tranexamic Acid on the Surgical Field in Primary Cleft Palate Surgery on Children—A Prospective, Randomized Clinical Study" @default.
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- W2034383336 doi "https://doi.org/10.1597/14-263" @default.
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