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• W2034387541 startingPage "7548" @default.
• W2034387541 abstract "Throughout different sensory systems, individual neurons integrate incoming signals over their receptive fields. The characteristics of this signal integration are crucial determinants for the neurons' functions. For ganglion cells in the vertebrate retina, receptive fields are characterized by the well-known center-surround structure and, although several studies have addressed spatial integration in the receptive field center, little is known about how visual signals are integrated in the surround. Therefore, we set out here to characterize signal integration and to identify relevant nonlinearities in the receptive field surround of ganglion cells in the isolated salamander retina by recording spiking activity with extracellular electrodes under visual stimulation of the center and surround. To quantify nonlinearities of spatial integration independently of subsequent nonlinearities of spike generation, we applied the technique of iso-response measurements as follows: using closed-loop experiments, we searched for different stimulus patterns in the surround that all reduced the center-evoked spiking activity by the same amount. The identified iso-response stimuli revealed strongly nonlinear spatial integration in the receptive field surrounds of all recorded cells. Furthermore, cell types that had been shown previously to have different nonlinearities in receptive field centers showed similar surround nonlinearities but differed systematically in the adaptive characteristics of the surround. Finally, we found that there is an optimal spatial scale of surround suppression; suppression was most effective when surround stimulation was organized into subregions of several hundred micrometers in diameter, indicating that the surround is composed of subunits that have strong center-surround organization themselves." @default.
• W2034387541 created "2016-06-24" @default.
• W2034387541 creator A5083821374 @default.
• W2034387541 creator A5086835913 @default.
• W2034387541 date "2014-05-28" @default.
• W2034387541 modified "2023-09-24" @default.
• W2034387541 title "Nonlinear Spatial Integration in the Receptive Field Surround of Retinal Ganglion Cells" @default.
• W2034387541 cites W1481789758 @default.
• W2034387541 cites W1555852936 @default.
• W2034387541 cites W1601532569 @default.
• W2034387541 cites W1612963976 @default.
• W2034387541 cites W1829998668 @default.
• W2034387541 cites W1897692605 @default.
• W2034387541 cites W1955574248 @default.
• W2034387541 cites W1965673217 @default.
• W2034387541 cites W1966121276 @default.
• W2034387541 cites W1967570565 @default.
• W2034387541 cites W1967983911 @default.
• W2034387541 cites W1968991669 @default.
• W2034387541 cites W1968991873 @default.
• W2034387541 cites W1974696991 @default.
• W2034387541 cites W1978359413 @default.
• W2034387541 cites W1980141249 @default.
• W2034387541 cites W1984644816 @default.
• W2034387541 cites W1988813033 @default.
• W2034387541 cites W1988849438 @default.
• W2034387541 cites W1991126324 @default.
• W2034387541 cites W1991297520 @default.
• W2034387541 cites W1994434699 @default.
• W2034387541 cites W1996568471 @default.
• W2034387541 cites W2002121574 @default.
• W2034387541 cites W2005298527 @default.
• W2034387541 cites W2008624261 @default.
• W2034387541 cites W2011860702 @default.
• W2034387541 cites W2013136684 @default.
• W2034387541 cites W2019723923 @default.
• W2034387541 cites W2021079169 @default.
• W2034387541 cites W2022186938 @default.
• W2034387541 cites W2026091672 @default.
• W2034387541 cites W2027446612 @default.
• W2034387541 cites W2028932310 @default.
• W2034387541 cites W2029137641 @default.
• W2034387541 cites W2032887453 @default.
• W2034387541 cites W2035989480 @default.
• W2034387541 cites W2037395945 @default.
• W2034387541 cites W2038334426 @default.
• W2034387541 cites W2040271055 @default.
• W2034387541 cites W2044514870 @default.
• W2034387541 cites W2044917446 @default.
• W2034387541 cites W2052787208 @default.
• W2034387541 cites W2055179977 @default.
• W2034387541 cites W2058483899 @default.
• W2034387541 cites W2059571588 @default.
• W2034387541 cites W2065176644 @default.
• W2034387541 cites W2065621419 @default.
• W2034387541 cites W2069011228 @default.
• W2034387541 cites W2069746024 @default.
• W2034387541 cites W2070456939 @default.
• W2034387541 cites W2071567206 @default.
• W2034387541 cites W2075864611 @default.
• W2034387541 cites W2076225732 @default.
• W2034387541 cites W2077105925 @default.
• W2034387541 cites W2077229035 @default.
• W2034387541 cites W2077424228 @default.
• W2034387541 cites W2077512689 @default.
• W2034387541 cites W2086140762 @default.
• W2034387541 cites W2087270663 @default.
• W2034387541 cites W2088931889 @default.
• W2034387541 cites W2089212217 @default.
• W2034387541 cites W2091900366 @default.
• W2034387541 cites W2092515857 @default.
• W2034387541 cites W2095087224 @default.
• W2034387541 cites W2097166988 @default.
• W2034387541 cites W2099616257 @default.
• W2034387541 cites W2109634313 @default.
• W2034387541 cites W2112455917 @default.
• W2034387541 cites W2117851116 @default.
• W2034387541 cites W2126471434 @default.
• W2034387541 cites W2130143700 @default.
• W2034387541 cites W2131113894 @default.
• W2034387541 cites W2135488337 @default.
• W2034387541 cites W2136067425 @default.
• W2034387541 cites W2137710832 @default.
• W2034387541 cites W2143895879 @default.
• W2034387541 cites W2159198041 @default.
• W2034387541 cites W2159659012 @default.
• W2034387541 cites W2160032358 @default.
• W2034387541 cites W2162489171 @default.
• W2034387541 cites W2163750597 @default.
• W2034387541 cites W2166635906 @default.
• W2034387541 cites W2169924703 @default.
• W2034387541 cites W2212384750 @default.
• W2034387541 cites W2305283737 @default.
• W2034387541 cites W2327841142 @default.
• W2034387541 cites W3106387966 @default.
• W2034387541 cites W68224751 @default.
• W2034387541 doi "https://doi.org/10.1523/jneurosci.0413-14.2014" @default.
• W2034387541 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6795248" @default.

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