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- W2034391131 abstract "Temperature shift experiments done on infectious centres reveal the existence of two classes of thermosenstive mutants. Early mutants are characterized by a defect in a necessary function during the first 24 h after inoculation at 20° C. On the contrary, late mutants are characterized by a defect in a function which is necessary after the first 24 h of infection. Two types of early mutants are defined and allow to distinguish two early steps of sigma virus cycle at 20°C. The temperature-sensitive period of the haP7 mutant characterizes the first step lasting from 0 to 9 h; the ts4 mutant has a temperature-sensitive period extending from 4 to 15 h and defines the second step. It is proposed that the viral genome replication takes place between 4 and 15 h. Analogy between the two types of early ts mutants of sigma virus and some ts mutants of vesicular stomatitis virus will be discussed in this paper." @default.
- W2034391131 created "2016-06-24" @default.
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- W2034391131 date "1980-04-01" @default.
- W2034391131 modified "2023-09-27" @default.
- W2034391131 title "Two types of early mutants among the temperature-sensitive mutants of drosophila sigma virus" @default.
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- W2034391131 doi "https://doi.org/10.1016/0769-2617(80)90027-1" @default.
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