Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034394466> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2034394466 endingPage "569" @default.
- W2034394466 startingPage "565" @default.
- W2034394466 abstract "The objective was to assess the effect of topically administered dexamethasone on peripheral nerve regeneration and functional recovery. Sixty male healthy white Wistar rats were divided into four experimental groups (n = 15), randomly: in transected group (TC), left sciatic nerve was transected and stumps were fixed in the adjacent muscle. In treatment group defect was bridged using a silicone tube (SIL/Dexa) filled with 10 μL dexamethasone (0.1 mg/kg). In silicone group (SIL), the tube was filled with phosphate-buffered saline alone. In sham-operated group (SHAM), sciatic nerve was exposed and manipulated. Each group was subdivided into three subgroups of five animals each and regenerated nerve fibres were studied 4, 8 and 12 weeks after surgery. Functional study, gastrocnemius muscle mass and morphometric indices confirmed faster recovery of regenerated axons in SIL/Dexa than SIL group (p < 0.05). In immunohistochemistry, location of reactions to S-100 in SIL/Dexa was clearly more positive than that in SIL group. When loaded in a silicone tube, dexamethasone improved functional recovery and morphometric indices of sciatic nerve. Topical application of this readily available agent offers the benefit of cost savings as well as avoiding the complications associated with systemic administration." @default.
- W2034394466 created "2016-06-24" @default.
- W2034394466 creator A5003702079 @default.
- W2034394466 creator A5035223701 @default.
- W2034394466 creator A5087685298 @default.
- W2034394466 date "2013-04-01" @default.
- W2034394466 modified "2023-10-16" @default.
- W2034394466 title "Dexamethasone topically accelerates peripheral nerve repair and target organ reinnervation: A transected sciatic nerve model in rat" @default.
- W2034394466 cites W1429378503 @default.
- W2034394466 cites W1969338596 @default.
- W2034394466 cites W1997745372 @default.
- W2034394466 cites W2001257321 @default.
- W2034394466 cites W2016306246 @default.
- W2034394466 cites W2026941166 @default.
- W2034394466 cites W2033207448 @default.
- W2034394466 cites W2037462205 @default.
- W2034394466 cites W2048263315 @default.
- W2034394466 cites W2052027207 @default.
- W2034394466 cites W2062781460 @default.
- W2034394466 cites W2064888696 @default.
- W2034394466 cites W2071042968 @default.
- W2034394466 cites W2076358382 @default.
- W2034394466 cites W2081405480 @default.
- W2034394466 cites W2087454739 @default.
- W2034394466 cites W2088608292 @default.
- W2034394466 cites W2099328349 @default.
- W2034394466 cites W2147164142 @default.
- W2034394466 cites W2147993472 @default.
- W2034394466 cites W2170118350 @default.
- W2034394466 cites W2333839540 @default.
- W2034394466 cites W2407597025 @default.
- W2034394466 doi "https://doi.org/10.1016/j.injury.2012.10.013" @default.
- W2034394466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23131678" @default.
- W2034394466 hasPublicationYear "2013" @default.
- W2034394466 type Work @default.
- W2034394466 sameAs 2034394466 @default.
- W2034394466 citedByCount "33" @default.
- W2034394466 countsByYear W20343944662014 @default.
- W2034394466 countsByYear W20343944662015 @default.
- W2034394466 countsByYear W20343944662016 @default.
- W2034394466 countsByYear W20343944662017 @default.
- W2034394466 countsByYear W20343944662018 @default.
- W2034394466 countsByYear W20343944662019 @default.
- W2034394466 countsByYear W20343944662020 @default.
- W2034394466 countsByYear W20343944662022 @default.
- W2034394466 countsByYear W20343944662023 @default.
- W2034394466 crossrefType "journal-article" @default.
- W2034394466 hasAuthorship W2034394466A5003702079 @default.
- W2034394466 hasAuthorship W2034394466A5035223701 @default.
- W2034394466 hasAuthorship W2034394466A5087685298 @default.
- W2034394466 hasConcept C105702510 @default.
- W2034394466 hasConcept C126322002 @default.
- W2034394466 hasConcept C141071460 @default.
- W2034394466 hasConcept C2775872116 @default.
- W2034394466 hasConcept C2776588550 @default.
- W2034394466 hasConcept C2776880756 @default.
- W2034394466 hasConcept C2777397205 @default.
- W2034394466 hasConcept C2779649809 @default.
- W2034394466 hasConcept C2779959927 @default.
- W2034394466 hasConcept C2780401358 @default.
- W2034394466 hasConcept C2781149210 @default.
- W2034394466 hasConcept C42219234 @default.
- W2034394466 hasConcept C71924100 @default.
- W2034394466 hasConceptScore W2034394466C105702510 @default.
- W2034394466 hasConceptScore W2034394466C126322002 @default.
- W2034394466 hasConceptScore W2034394466C141071460 @default.
- W2034394466 hasConceptScore W2034394466C2775872116 @default.
- W2034394466 hasConceptScore W2034394466C2776588550 @default.
- W2034394466 hasConceptScore W2034394466C2776880756 @default.
- W2034394466 hasConceptScore W2034394466C2777397205 @default.
- W2034394466 hasConceptScore W2034394466C2779649809 @default.
- W2034394466 hasConceptScore W2034394466C2779959927 @default.
- W2034394466 hasConceptScore W2034394466C2780401358 @default.
- W2034394466 hasConceptScore W2034394466C2781149210 @default.
- W2034394466 hasConceptScore W2034394466C42219234 @default.
- W2034394466 hasConceptScore W2034394466C71924100 @default.
- W2034394466 hasIssue "4" @default.
- W2034394466 hasLocation W20343944661 @default.
- W2034394466 hasLocation W20343944662 @default.
- W2034394466 hasOpenAccess W2034394466 @default.
- W2034394466 hasPrimaryLocation W20343944661 @default.
- W2034394466 hasRelatedWork W1542533968 @default.
- W2034394466 hasRelatedWork W2010396028 @default.
- W2034394466 hasRelatedWork W2034394466 @default.
- W2034394466 hasRelatedWork W2106027558 @default.
- W2034394466 hasRelatedWork W2167782181 @default.
- W2034394466 hasRelatedWork W2356458430 @default.
- W2034394466 hasRelatedWork W2357916362 @default.
- W2034394466 hasRelatedWork W2565378963 @default.
- W2034394466 hasRelatedWork W2901335917 @default.
- W2034394466 hasRelatedWork W3158663320 @default.
- W2034394466 hasVolume "44" @default.
- W2034394466 isParatext "false" @default.
- W2034394466 isRetracted "false" @default.
- W2034394466 magId "2034394466" @default.
- W2034394466 workType "article" @default.