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- W2034402972 abstract "This study was conducted to investigate the prevalence and genotypes of extended-spectrum <TEX>${beta}$</TEX>-lactamase (ESBL) in 377 Escherichia coli isolated from healthy and sick animals. Two isolates (0.5%), each of which were isolated from diseased swine and chicken, respectively, were confirmed as ESBL producing isolates by double disk synergy test, and showed a multidrug resistant phenotype. Minimum inhibitory concentration of cefotaxime for the two ESBL producing isolates were 3~4 times higher than those of ceftazidime, respectively. By PCR and sequencing, one isolate from swine have both <TEX>$bla_{CTX-15}$</TEX> and <TEX>$bla_{TEM-1}$</TEX>, and one isolate from chicken have <TEX>$bla_{CTX-15}$</TEX> and <TEX>$bla_{TEM-116}$</TEX>. Also, these genes were transferred to E. coli J53 by conjugation. These two isolates showed unrelated pulsed-field gel electrophoresis. To our knowledge, this is the first time that <TEX>$bla_{TEM-116}$</TEX> gene was identified in E. coli isolated from animals in Korea. These results suggest more prudent use of third- generation cephalosporins, and surveillance and monitoring for ESBL producing E. coli in both animals and their environments should be necessary." @default.
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- W2034402972 date "2011-03-30" @default.
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- W2034402972 title "Detection of CTX-M and TEM type extended-spectrum β-lactamases in Escherichia coli isolated from livestocks in Korea" @default.
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- W2034402972 doi "https://doi.org/10.7853/kjvs.2011.34.1.037" @default.
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