FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034404116> ?p ?o ?g. }

• W2034404116 endingPage "333" @default.
• W2034404116 startingPage "328" @default.
• W2034404116 abstract "OBJECTIVE: To carry out a comprehensive field investigation to evaluate various conventional and recently developed biomarkers for exposure to low concentrations of benzene. METHODS: Analyses were carried out on environmental air, unmetabolised benzene in blood and urine, urinary trans, transmuconic acid, and three major phenolic metabolites of benzene: phenol, catechol, and hydroquinone. Validations of these biomarkers were performed on 131 never smokers occupationally exposed to the time weighed average benzene concentration of 0.25 ppm (range, 0.01 to 3.5 ppm). RESULTS: Among the six biomarkers studied, unmetabolised benzene in urine correlated best with environmental benzene concentration (correlation coefficient, r = 0.76), followed by benzene in blood (r = 0.64). When urinary metabolites were compared with environmental benzene, trans, trans-muconic acid showed a close correlation (r = 0.53) followed by hydroquinone (r = 0.44), and to a lesser extent with urinary phenol (r = 0.38). No correlation was found between catechol and environmental benzene concentrations. Although unmetabolised benzene in urine correlates best with benzene exposure, owing to serious technical drawbacks, its use is limited. Among the metabolites, trans, trans-muconic acid seems to be more reliable than other phenolic compounds. Nevertheless, detailed analyses failed to show that it is specific for monitoring benzene exposures below 0.25 ppm. CONCLUSION: The overall results suggest that most of the currently available biomarkers are unable to provide sufficient specificity for monitoring of low concentrations of benzene exposure. If a lower occupational exposure limit for benzene is to be considered, the reliability of the biomarker and the technical limitations of measurements have to be carefully validated." @default.
• W2034404116 created "2016-06-24" @default.
• W2034404116 creator A5003150563 @default.
• W2034404116 creator A5009749498 @default.
• W2034404116 creator A5021223767 @default.
• W2034404116 creator A5041560464 @default.
• W2034404116 creator A5045967813 @default.
• W2034404116 creator A5055260977 @default.
• W2034404116 creator A5086986688 @default.
• W2034404116 date "1996-05-01" @default.
• W2034404116 modified "2023-10-01" @default.
• W2034404116 title "Biomarkers of exposure to low concentrations of benzene: a field assessment." @default.
• W2034404116 cites W1965174529 @default.
• W2034404116 cites W1965657406 @default.
• W2034404116 cites W1966118375 @default.
• W2034404116 cites W1969957976 @default.
• W2034404116 cites W1974149498 @default.
• W2034404116 cites W1979444141 @default.
• W2034404116 cites W1988042891 @default.
• W2034404116 cites W1998888603 @default.
• W2034404116 cites W2024409430 @default.
• W2034404116 cites W2026406983 @default.
• W2034404116 cites W2037031364 @default.
• W2034404116 cites W2041947927 @default.
• W2034404116 cites W2054116562 @default.
• W2034404116 cites W2073244181 @default.
• W2034404116 cites W2093540827 @default.
• W2034404116 cites W2112842611 @default.
• W2034404116 cites W2122250929 @default.
• W2034404116 cites W2152234447 @default.
• W2034404116 cites W2157720060 @default.
• W2034404116 doi "https://doi.org/10.1136/oem.53.5.328" @default.
• W2034404116 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1128475" @default.
• W2034404116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8673180" @default.
• W2034404116 hasPublicationYear "1996" @default.
• W2034404116 type Work @default.
• W2034404116 sameAs 2034404116 @default.
• W2034404116 citedByCount "92" @default.
• W2034404116 countsByYear W20344041162012 @default.
• W2034404116 countsByYear W20344041162013 @default.
• W2034404116 countsByYear W20344041162017 @default.
• W2034404116 countsByYear W20344041162018 @default.
• W2034404116 countsByYear W20344041162019 @default.
• W2034404116 countsByYear W20344041162021 @default.
• W2034404116 countsByYear W20344041162022 @default.
• W2034404116 crossrefType "journal-article" @default.
• W2034404116 hasAuthorship W2034404116A5003150563 @default.
• W2034404116 hasAuthorship W2034404116A5009749498 @default.
• W2034404116 hasAuthorship W2034404116A5021223767 @default.
• W2034404116 hasAuthorship W2034404116A5041560464 @default.
• W2034404116 hasAuthorship W2034404116A5045967813 @default.
• W2034404116 hasAuthorship W2034404116A5055260977 @default.
• W2034404116 hasAuthorship W2034404116A5086986688 @default.
• W2034404116 hasBestOaLocation W20344041161 @default.
• W2034404116 hasConcept C107872376 @default.
• W2034404116 hasConcept C119128265 @default.
• W2034404116 hasConcept C126322002 @default.
• W2034404116 hasConcept C178790620 @default.
• W2034404116 hasConcept C185592680 @default.
• W2034404116 hasConcept C2776234857 @default.
• W2034404116 hasConcept C2777550763 @default.
• W2034404116 hasConcept C2777691172 @default.
• W2034404116 hasConcept C2777702071 @default.
• W2034404116 hasConcept C2777713698 @default.
• W2034404116 hasConcept C2780026642 @default.
• W2034404116 hasConcept C2781197716 @default.
• W2034404116 hasConcept C43617362 @default.
• W2034404116 hasConcept C55493867 @default.
• W2034404116 hasConcept C71924100 @default.
• W2034404116 hasConcept C77411442 @default.
• W2034404116 hasConceptScore W2034404116C107872376 @default.
• W2034404116 hasConceptScore W2034404116C119128265 @default.
• W2034404116 hasConceptScore W2034404116C126322002 @default.
• W2034404116 hasConceptScore W2034404116C178790620 @default.
• W2034404116 hasConceptScore W2034404116C185592680 @default.
• W2034404116 hasConceptScore W2034404116C2776234857 @default.
• W2034404116 hasConceptScore W2034404116C2777550763 @default.
• W2034404116 hasConceptScore W2034404116C2777691172 @default.
• W2034404116 hasConceptScore W2034404116C2777702071 @default.
• W2034404116 hasConceptScore W2034404116C2777713698 @default.
• W2034404116 hasConceptScore W2034404116C2780026642 @default.
• W2034404116 hasConceptScore W2034404116C2781197716 @default.
• W2034404116 hasConceptScore W2034404116C43617362 @default.
• W2034404116 hasConceptScore W2034404116C55493867 @default.
• W2034404116 hasConceptScore W2034404116C71924100 @default.
• W2034404116 hasConceptScore W2034404116C77411442 @default.
• W2034404116 hasIssue "5" @default.
• W2034404116 hasLocation W20344041161 @default.
• W2034404116 hasLocation W20344041162 @default.
• W2034404116 hasLocation W20344041163 @default.
• W2034404116 hasLocation W20344041164 @default.
• W2034404116 hasOpenAccess W2034404116 @default.
• W2034404116 hasPrimaryLocation W20344041161 @default.
• W2034404116 hasRelatedWork W2040368308 @default.
• W2034404116 hasRelatedWork W2063145940 @default.
• W2034404116 hasRelatedWork W2085394310 @default.
• W2034404116 hasRelatedWork W2098662035 @default.
• W2034404116 hasRelatedWork W2230199162 @default.

• next