FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034404865> ?p ?o ?g. }

• W2034404865 endingPage "370" @default.
• W2034404865 startingPage "363" @default.
• W2034404865 abstract "Since the rediscovery of brown adipose tissue (BAT) in adult human subjects in 2007, there has been a dramatic resurgence in research interest in its role in heat production and energy balance. This has coincided with a reassessment of the origins of BAT and the suggestion that brown preadipocytes could share a common lineage with skeletal myoblasts. In precocial newborns, such as sheep, the onset of non-shivering thermogenesis through activation of the BAT-specific uncoupling protein 1 (UCP1) is essential for effective adaptation to the cold exposure of the extra-uterine environment. This is mediated by a combination of endocrine adaptations which accompany normal parturition at birth and further endocrine stimulation from the mother's milk. Three distinct adipose depots have been identified in all species studied to date. These contain either primarily white, primarily brown or a mix of brown and white adipocytes. The latter tissue type is present, at least, in the fetus and, thereafter, appears to take on the characteristics of white adipose tissue during postnatal development. It is becoming apparent that a range of organ-specific mechanisms can promote UCP1 expression. They include the liver, heart and skeletal muscle, and involve unique endocrine systems that are stimulated by cold exposure and/or exercise. These multiple pathways that promote BAT function vary with age and between species that may determine the potential to be manipulated in early life. Such interventions could modify, or reverse, the normal ontogenic pathway by which BAT disappears after birth, thereby facilitating BAT thermogenesis through the life cycle." @default.
• W2034404865 created "2016-06-24" @default.
• W2034404865 creator A5040978436 @default.
• W2034404865 creator A5070732752 @default.
• W2034404865 creator A5090256187 @default.
• W2034404865 date "2012-06-18" @default.
• W2034404865 modified "2023-10-08" @default.
• W2034404865 title "Adipose tissue development during early life: novel insights into energy balance from small and large mammals" @default.
• W2034404865 cites W1515998049 @default.
• W2034404865 cites W1518413690 @default.
• W2034404865 cites W1768227580 @default.
• W2034404865 cites W177415238 @default.
• W2034404865 cites W1800166075 @default.
• W2034404865 cites W1964023191 @default.
• W2034404865 cites W1964347318 @default.
• W2034404865 cites W1965079305 @default.
• W2034404865 cites W1967680954 @default.
• W2034404865 cites W1967898940 @default.
• W2034404865 cites W1971680857 @default.
• W2034404865 cites W1971799323 @default.
• W2034404865 cites W1972836378 @default.
• W2034404865 cites W1973863797 @default.
• W2034404865 cites W1979026577 @default.
• W2034404865 cites W1981525131 @default.
• W2034404865 cites W1981706410 @default.
• W2034404865 cites W1981723498 @default.
• W2034404865 cites W1981785232 @default.
• W2034404865 cites W1987906273 @default.
• W2034404865 cites W1988869711 @default.
• W2034404865 cites W1992134118 @default.
• W2034404865 cites W1995862250 @default.
• W2034404865 cites W2004192853 @default.
• W2034404865 cites W2005827500 @default.
• W2034404865 cites W2006888533 @default.
• W2034404865 cites W2009591361 @default.
• W2034404865 cites W2010255616 @default.
• W2034404865 cites W2014268090 @default.
• W2034404865 cites W2014312065 @default.
• W2034404865 cites W2028960534 @default.
• W2034404865 cites W2040328785 @default.
• W2034404865 cites W2040384492 @default.
• W2034404865 cites W2043531340 @default.
• W2034404865 cites W2056631165 @default.
• W2034404865 cites W2068842027 @default.
• W2034404865 cites W2071304205 @default.
• W2034404865 cites W2073582448 @default.
• W2034404865 cites W2078057245 @default.
• W2034404865 cites W2079204610 @default.
• W2034404865 cites W2080098347 @default.
• W2034404865 cites W2085397620 @default.
• W2034404865 cites W2087386910 @default.
• W2034404865 cites W2089759898 @default.
• W2034404865 cites W2093825860 @default.
• W2034404865 cites W2097220604 @default.
• W2034404865 cites W2098373558 @default.
• W2034404865 cites W2098457930 @default.
• W2034404865 cites W2101726254 @default.
• W2034404865 cites W2104827888 @default.
• W2034404865 cites W2110645284 @default.
• W2034404865 cites W2111390745 @default.
• W2034404865 cites W2114525053 @default.
• W2034404865 cites W2119162479 @default.
• W2034404865 cites W2121560695 @default.
• W2034404865 cites W2124622918 @default.
• W2034404865 cites W2126398723 @default.
• W2034404865 cites W2127173832 @default.
• W2034404865 cites W2132358997 @default.
• W2034404865 cites W2135531862 @default.
• W2034404865 cites W2141543212 @default.
• W2034404865 cites W2145142659 @default.
• W2034404865 cites W2152915643 @default.
• W2034404865 cites W2153081066 @default.
• W2034404865 cites W2154599014 @default.
• W2034404865 cites W2155488648 @default.
• W2034404865 cites W2157161256 @default.
• W2034404865 cites W2159456688 @default.
• W2034404865 cites W2161286935 @default.
• W2034404865 cites W2163353061 @default.
• W2034404865 cites W2164489689 @default.
• W2034404865 cites W2164652793 @default.
• W2034404865 cites W2166946889 @default.
• W2034404865 cites W2169312374 @default.
• W2034404865 cites W2301940626 @default.
• W2034404865 cites W2314646581 @default.
• W2034404865 cites W259234919 @default.
• W2034404865 cites W4252436368 @default.
• W2034404865 doi "https://doi.org/10.1017/s0029665112000584" @default.
• W2034404865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22704581" @default.
• W2034404865 hasPublicationYear "2012" @default.
• W2034404865 type Work @default.
• W2034404865 sameAs 2034404865 @default.
• W2034404865 citedByCount "41" @default.
• W2034404865 countsByYear W20344048652012 @default.
• W2034404865 countsByYear W20344048652013 @default.
• W2034404865 countsByYear W20344048652014 @default.
• W2034404865 countsByYear W20344048652015 @default.
• W2034404865 countsByYear W20344048652016 @default.
• W2034404865 countsByYear W20344048652017 @default.

• next