Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034405454> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2034405454 endingPage "521" @default.
- W2034405454 startingPage "520" @default.
- W2034405454 abstract "To describe a potential association between male infertility and valproate (VPA) exposure. VPA has been implicated in the development of polycystic ovarian disease and subsequent menstrual and infertility problems in women with epilepsy. Infertility has been well described in population-based studies of persons with epilepsy. The low marital rates for men with epilepsy have previously been thought to play a major contributing role.We report a case of a 32-year-old man whose wife and he were able to bear a child before the development of his epilepsy. With VPA monotherapy, the family were unable to conceive despite 4 years of unprotected intercourse. An infertility evaluation of the man revealed a very low sperm count of < 50,000/ml, no motile sperm, < 10% viability, and 100% with abnormal structure. Follicle-stimulating hormone, luteinizing hormone, and testosterone levels were normal.Felbamate (FBM) was initiated and VPA discontinued for improved seizure control. Within 4 months, the couple conceived their second child. A seminal analysis revealed a sperm count of > 16 million, 50% motility, 78% viability, and 72% with abnormal structure.One must be cautious in extrapolating from a case report, but these findings strongly suggest a direct effect of VPA on spermatic structure and function." @default.
- W2034405454 created "2016-06-24" @default.
- W2034405454 creator A5005396213 @default.
- W2034405454 creator A5026256625 @default.
- W2034405454 date "1999-04-01" @default.
- W2034405454 modified "2023-10-02" @default.
- W2034405454 title "Male Infertility: Possible Association with Valproate Exposure" @default.
- W2034405454 cites W1996427998 @default.
- W2034405454 cites W2008317657 @default.
- W2034405454 cites W2079769181 @default.
- W2034405454 cites W2136432700 @default.
- W2034405454 cites W2338906118 @default.
- W2034405454 cites W4251533758 @default.
- W2034405454 doi "https://doi.org/10.1111/j.1528-1157.1999.tb00752.x" @default.
- W2034405454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10219283" @default.
- W2034405454 hasPublicationYear "1999" @default.
- W2034405454 type Work @default.
- W2034405454 sameAs 2034405454 @default.
- W2034405454 citedByCount "39" @default.
- W2034405454 countsByYear W20344054542013 @default.
- W2034405454 countsByYear W20344054542015 @default.
- W2034405454 countsByYear W20344054542016 @default.
- W2034405454 countsByYear W20344054542017 @default.
- W2034405454 countsByYear W20344054542019 @default.
- W2034405454 countsByYear W20344054542020 @default.
- W2034405454 countsByYear W20344054542021 @default.
- W2034405454 countsByYear W20344054542023 @default.
- W2034405454 crossrefType "journal-article" @default.
- W2034405454 hasAuthorship W2034405454A5005396213 @default.
- W2034405454 hasAuthorship W2034405454A5026256625 @default.
- W2034405454 hasBestOaLocation W20344054541 @default.
- W2034405454 hasConcept C118552586 @default.
- W2034405454 hasConcept C126322002 @default.
- W2034405454 hasConcept C134018914 @default.
- W2034405454 hasConcept C16685009 @default.
- W2034405454 hasConcept C2777338322 @default.
- W2034405454 hasConcept C2777391703 @default.
- W2034405454 hasConcept C2777632594 @default.
- W2034405454 hasConcept C2777688143 @default.
- W2034405454 hasConcept C2778186239 @default.
- W2034405454 hasConcept C2778575703 @default.
- W2034405454 hasConcept C2779234561 @default.
- W2034405454 hasConcept C2779279991 @default.
- W2034405454 hasConcept C2781087480 @default.
- W2034405454 hasConcept C2908647359 @default.
- W2034405454 hasConcept C29456083 @default.
- W2034405454 hasConcept C3018442814 @default.
- W2034405454 hasConcept C42407357 @default.
- W2034405454 hasConcept C54355233 @default.
- W2034405454 hasConcept C555293320 @default.
- W2034405454 hasConcept C71315377 @default.
- W2034405454 hasConcept C71924100 @default.
- W2034405454 hasConcept C86803240 @default.
- W2034405454 hasConcept C99454951 @default.
- W2034405454 hasConceptScore W2034405454C118552586 @default.
- W2034405454 hasConceptScore W2034405454C126322002 @default.
- W2034405454 hasConceptScore W2034405454C134018914 @default.
- W2034405454 hasConceptScore W2034405454C16685009 @default.
- W2034405454 hasConceptScore W2034405454C2777338322 @default.
- W2034405454 hasConceptScore W2034405454C2777391703 @default.
- W2034405454 hasConceptScore W2034405454C2777632594 @default.
- W2034405454 hasConceptScore W2034405454C2777688143 @default.
- W2034405454 hasConceptScore W2034405454C2778186239 @default.
- W2034405454 hasConceptScore W2034405454C2778575703 @default.
- W2034405454 hasConceptScore W2034405454C2779234561 @default.
- W2034405454 hasConceptScore W2034405454C2779279991 @default.
- W2034405454 hasConceptScore W2034405454C2781087480 @default.
- W2034405454 hasConceptScore W2034405454C2908647359 @default.
- W2034405454 hasConceptScore W2034405454C29456083 @default.
- W2034405454 hasConceptScore W2034405454C3018442814 @default.
- W2034405454 hasConceptScore W2034405454C42407357 @default.
- W2034405454 hasConceptScore W2034405454C54355233 @default.
- W2034405454 hasConceptScore W2034405454C555293320 @default.
- W2034405454 hasConceptScore W2034405454C71315377 @default.
- W2034405454 hasConceptScore W2034405454C71924100 @default.
- W2034405454 hasConceptScore W2034405454C86803240 @default.
- W2034405454 hasConceptScore W2034405454C99454951 @default.
- W2034405454 hasIssue "4" @default.
- W2034405454 hasLocation W20344054541 @default.
- W2034405454 hasLocation W20344054542 @default.
- W2034405454 hasOpenAccess W2034405454 @default.
- W2034405454 hasPrimaryLocation W20344054541 @default.
- W2034405454 hasRelatedWork W1986311037 @default.
- W2034405454 hasRelatedWork W1988486434 @default.
- W2034405454 hasRelatedWork W1999611386 @default.
- W2034405454 hasRelatedWork W1999831221 @default.
- W2034405454 hasRelatedWork W2012502375 @default.
- W2034405454 hasRelatedWork W2047880909 @default.
- W2034405454 hasRelatedWork W2064034534 @default.
- W2034405454 hasRelatedWork W2073502422 @default.
- W2034405454 hasRelatedWork W2163989763 @default.
- W2034405454 hasRelatedWork W2313856518 @default.
- W2034405454 hasVolume "40" @default.
- W2034405454 isParatext "false" @default.
- W2034405454 isRetracted "false" @default.
- W2034405454 magId "2034405454" @default.
- W2034405454 workType "article" @default.