FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034405939> ?p ?o ?g. }

• W2034405939 endingPage "8783" @default.
• W2034405939 startingPage "8778" @default.
• W2034405939 abstract "The recent completion of the deletion of all of the nonessential genes in budding yeast has provided a powerful new way of determining those genes that affect the sensitivity of this organism to cytotoxic agents. We have used this system to test the hypothesis that genes whose transcription is increased after DNA damage are important for the survival to that damage. We used a pool of 4,627 diploid strains each with homozygous deletion of a nonessential gene to identify those genes that are important for the survival of yeast to four DNA-damaging agents: ionizing radiation, UV radiation, and exposure to cisplatin or to hydrogen peroxide. In addition we measured the transcriptional response of the wild-type parental strain to the same DNA-damaging agents. We found no relationship between the genes necessary for survival to the DNA-damaging agents and those genes whose transcription is increased after exposure. These data show that few, if any, of the genes involved in repairing the DNA lesions produced in this study, including double-strand breaks, pyrimidine dimers, single-strand breaks, base damage, and DNA cross-links, are induced in response to toxic doses of the agents that produce these lesions. This finding suggests that the enzymes necessary for the repair of these lesions are at sufficient levels within the cell. The data also suggest that the nature of the lesions produced by DNA-damaging agents cannot easily be deduced from gene expression profiling." @default.
• W2034405939 created "2016-06-24" @default.
• W2034405939 creator A5019091122 @default.
• W2034405939 creator A5021418585 @default.
• W2034405939 creator A5022830611 @default.
• W2034405939 creator A5027866777 @default.
• W2034405939 creator A5028157309 @default.
• W2034405939 creator A5044491731 @default.
• W2034405939 creator A5060854154 @default.
• W2034405939 date "2002-06-19" @default.
• W2034405939 modified "2023-10-15" @default.
• W2034405939 title "Transcriptional response of <i>Saccharomyces cerevisiae</i> to DNA-damaging agents does not identify the genes that protect against these agents" @default.
• W2034405939 cites W1480404031 @default.
• W2034405939 cites W1495406308 @default.
• W2034405939 cites W1571917377 @default.
• W2034405939 cites W1651215666 @default.
• W2034405939 cites W1822785715 @default.
• W2034405939 cites W1880623221 @default.
• W2034405939 cites W1949238489 @default.
• W2034405939 cites W1965679838 @default.
• W2034405939 cites W1982870743 @default.
• W2034405939 cites W1985064413 @default.
• W2034405939 cites W2000074317 @default.
• W2034405939 cites W2003239553 @default.
• W2034405939 cites W2038437697 @default.
• W2034405939 cites W2039024251 @default.
• W2034405939 cites W2042902860 @default.
• W2034405939 cites W2058761693 @default.
• W2034405939 cites W2064208261 @default.
• W2034405939 cites W2071721857 @default.
• W2034405939 cites W2097413644 @default.
• W2034405939 cites W2100258190 @default.
• W2034405939 cites W2103453943 @default.
• W2034405939 cites W2109970232 @default.
• W2034405939 cites W2118567506 @default.
• W2034405939 cites W2137683543 @default.
• W2034405939 cites W2140948740 @default.
• W2034405939 cites W2146264532 @default.
• W2034405939 cites W2147246240 @default.
• W2034405939 cites W2155675863 @default.
• W2034405939 cites W2157795344 @default.
• W2034405939 cites W2162298790 @default.
• W2034405939 cites W2162735386 @default.
• W2034405939 cites W2164125718 @default.
• W2034405939 cites W2165011536 @default.
• W2034405939 cites W4246651551 @default.
• W2034405939 cites W4253445775 @default.
• W2034405939 cites W4294107304 @default.
• W2034405939 doi "https://doi.org/10.1073/pnas.132275199" @default.
• W2034405939 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/124375" @default.
• W2034405939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12077312" @default.
• W2034405939 hasPublicationYear "2002" @default.
• W2034405939 type Work @default.
• W2034405939 sameAs 2034405939 @default.
• W2034405939 citedByCount "232" @default.
• W2034405939 countsByYear W20344059392012 @default.
• W2034405939 countsByYear W20344059392013 @default.
• W2034405939 countsByYear W20344059392014 @default.
• W2034405939 countsByYear W20344059392015 @default.
• W2034405939 countsByYear W20344059392016 @default.
• W2034405939 countsByYear W20344059392017 @default.
• W2034405939 countsByYear W20344059392018 @default.
• W2034405939 countsByYear W20344059392019 @default.
• W2034405939 countsByYear W20344059392020 @default.
• W2034405939 countsByYear W20344059392021 @default.
• W2034405939 countsByYear W20344059392022 @default.
• W2034405939 countsByYear W20344059392023 @default.
• W2034405939 crossrefType "journal-article" @default.
• W2034405939 hasAuthorship W2034405939A5019091122 @default.
• W2034405939 hasAuthorship W2034405939A5021418585 @default.
• W2034405939 hasAuthorship W2034405939A5022830611 @default.
• W2034405939 hasAuthorship W2034405939A5027866777 @default.
• W2034405939 hasAuthorship W2034405939A5028157309 @default.
• W2034405939 hasAuthorship W2034405939A5044491731 @default.
• W2034405939 hasAuthorship W2034405939A5060854154 @default.
• W2034405939 hasBestOaLocation W20344059392 @default.
• W2034405939 hasConcept C104317684 @default.
• W2034405939 hasConcept C134935766 @default.
• W2034405939 hasConcept C138885662 @default.
• W2034405939 hasConcept C143425029 @default.
• W2034405939 hasConcept C153911025 @default.
• W2034405939 hasConcept C179926584 @default.
• W2034405939 hasConcept C2777576037 @default.
• W2034405939 hasConcept C41895202 @default.
• W2034405939 hasConcept C54355233 @default.
• W2034405939 hasConcept C552990157 @default.
• W2034405939 hasConcept C86803240 @default.
• W2034405939 hasConceptScore W2034405939C104317684 @default.
• W2034405939 hasConceptScore W2034405939C134935766 @default.
• W2034405939 hasConceptScore W2034405939C138885662 @default.
• W2034405939 hasConceptScore W2034405939C143425029 @default.
• W2034405939 hasConceptScore W2034405939C153911025 @default.
• W2034405939 hasConceptScore W2034405939C179926584 @default.
• W2034405939 hasConceptScore W2034405939C2777576037 @default.
• W2034405939 hasConceptScore W2034405939C41895202 @default.
• W2034405939 hasConceptScore W2034405939C54355233 @default.
• W2034405939 hasConceptScore W2034405939C552990157 @default.
• W2034405939 hasConceptScore W2034405939C86803240 @default.

• next