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- W2034426706 abstract "This communication completes this series of investigations. Ten carbinolamines derived from 6:7-dimethylquinoline and based on the quinine model are described. Three of the substances containing the 2-phenyl-6:7-dimethylquinoline nucleus show antiplasmodial activity on malaria in canaries much superior to the activity of quinine. The 6:7-dimethyi groups present in these compounds show a structural affinity with riboflavin but the antiplasmodial results are not favourable to the view that riboflavin-antagonism plays any significant part in the mechanism of action of these active bases." @default.
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- W2034426706 date "1948-10-26" @default.
- W2034426706 modified "2023-10-16" @default.
- W2034426706 title "Antiplasmodial action and chemical constitution IX. Carbinolamines derived from 6:7-dimethylquinoline" @default.
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- W2034426706 doi "https://doi.org/10.1098/rspb.1948.0011" @default.
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