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• W2034450071 abstract "The ventral noradrenergic bundle (VB) was mapped for self-stimulation throughout the region of its separation from the dorsal noradrenergic bundle in the mesencephalon of the rat. Eleven positive electrodes were located in the VB at sites clearly caudal to all known dopamine cell groups. Since the activation of dopamine neurons or other noradrenergic systems by current spread could be ruled out, the self-stimulation behavior was attributed to the activation of noradrenergic fibers in the VB itself. The cells of origin of these fibers were not determined, but it is probable from other evidence that noradrenergic cells from groups A6 and A7 were mainly involved. Twenty-nine electrodes in rostral VB sites yielded significantly higher maximum self-stimulation rates than the 11 caudal VB electrodes. The higher rates observed at rostral VB sites were attributed to: (a) the simultaneous activation of dorsal bundle and periventricular noradrenergic reward components that join the VB via the tegmental radiations, (b) the simultaneous activation of dopaminergic systems in the region of the substantia nigra, and (c) reduction of caudal VB rates by the simultaneous activation of directly-demonstrated escape systems." @default.
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• W2034450071 date "1974-11-01" @default.
• W2034450071 modified "2023-09-25" @default.
• W2034450071 title "Self-stimulation in the mesencephalic trajectory of the ventral noradrenergic bundle" @default.
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• W2034450071 doi "https://doi.org/10.1016/0006-8993(74)90484-3" @default.
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