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• W2034452843 abstract "Pacing and Clinical ElectrophysiologyVolume 8, Issue 2 p. 242-254 Appropriate Diagnostic Studies for Sinus Node Dysfunction HRAYR S KARAGUEUZIAN, Corresponding Author HRAYR S KARAGUEUZIAN Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaAddress for correspondence: Hrayr S. Karagueuzian, Ph.D., Ce dars-Sinai Medical Center, 8730 Beverly Boulevard, Halper Bldg., Los AngeieH, California 90048 USA.Search for more papers by this authorJAY L. JORDAN, JAY L. JORDAN Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorKAORU SUGI, KAORU SUGI Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorMASAO OHTA, MASAO OHTA Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorELI GANG, ELI GANG Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorTHOMAS PETER, THOMAS PETER Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorWILLIAM J. MANDEL, WILLIAM J. MANDEL Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this author HRAYR S KARAGUEUZIAN, Corresponding Author HRAYR S KARAGUEUZIAN Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaAddress for correspondence: Hrayr S. Karagueuzian, Ph.D., Ce dars-Sinai Medical Center, 8730 Beverly Boulevard, Halper Bldg., Los AngeieH, California 90048 USA.Search for more papers by this authorJAY L. JORDAN, JAY L. JORDAN Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorKAORU SUGI, KAORU SUGI Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorMASAO OHTA, MASAO OHTA Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorELI GANG, ELI GANG Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorTHOMAS PETER, THOMAS PETER Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this authorWILLIAM J. MANDEL, WILLIAM J. MANDEL Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CaliforniaSearch for more papers by this author First published: March 1985 https://doi.org/10.1111/j.1540-8159.1985.tb05756.xCitations: 8 Supported in part by ECHO Research Fund of Cedars-Sinai Medical Center, H.S. Karagueuzian is the recipient of Research Career Development Award No. HL 01293–01, National Heart Lung Blood Institute, Bethesda, Maryland. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Ferrer, M.I.: Sick sinus syndrome in atrial disease. JAMA, 206: 645, 1968. 2 Goldberg, A.N., Moran, J.F., Resnekov, L.: Multi stage electrocardiographic exercise tests. Am. J. Cardiol., 26: 84, 1970. 3 Holden, W., McAnulty, J.H., Rahimtoola, S.H.: Characterization of heart rate response to exercise in sick sinus syndrome. Br. Heart J., 40: 923, 1978. 4 Mandel, W.J., Hayakawa, H., Allen, H.N., et al.: Assessment of sinus node function in patients with the sick sinus syndrome. Circulation. 46: 761, 1972. 5 Grant, D., Shaw, D.B.: Sinus bradycardia. Br. Heart J., 33: 742, 1971. 6 Abbott, J.A., Hirschheld, D.S., Kumkel, F.W., et al.: Graded exercise testing in patients with sinus node dysfunction. Am. J. Med., 62: 330, 1977. 7 Ferrer, M.I.: The sick sinus syndrome. Mount Kisco , New York , Futura Publishing Co., 1974. 8 Agruss, N.S., Rosin. E.Y., Adolph, R.J., et al.: Sig nificance of chronic sinus bradycardia in elderly people. Circulation, 46: 924, 1972. 9 Thorman, J., Schwarz, F., Ensslen, R., et al.: Vagal tone, significance of electrophysiologic findings and clinical course in symptomatic sinus node dys function. Am. Heart J., 95: 725, 1978. 10 Scarpa, W.J.: The sick sinus syndrome. Am. Heart J, 92: 648, 1976. 11 Narula, O.S., Samet, P., Javier, R.F.: Significance of sinus node recovery time. Circulation, 45: 140, 1972. 12 Mandel, W.J., Lake, M.M., Obayashi, K.: Sinus node function: Evaluation in patients with and without sinus node disease. Arch. Intern. Med., 133: 388, 1975. 13 Eckberg, D.L., Drabinsky, M., Braunwald, E.: De fective cardiac parasympathetic control in patients with heart disease. N. Engl. J. Med., 285: 877, 1971. 14 Karagueuzian, H.S., Mandel, W.J.: The effects of drugs on sinus node function. In A Masoni and P. Alboni, (eds.): Cardiac Electrophysiology Today. New York , Academic Press, 1982, p. 123. 15 Jordan, J.L., Yamagushi, I., Mandel, W.J.: The sick sinus syndrome pathophysiology, significance and treatment. Cardiol. Dig., 12: 11, 1977. 16 Gaffney, J.B., Wasserman, A.G., Rotsztian, A., et al.: Sick sinus syndrome: Mechanisms and man agement. In A. Castellanos, (ed.): Cardiac Arrhyth mias—Mechanisms and Management, Philadelphia , F.A, Davis, 1980, p, 25. 17 Narula, O.S., Vasquez, M., Shanta, N., et al.: Effect of propranolol on normal and abnormal sinus node function. In F.I.M. Bonke, (ed.): The Sinus Node: Structure, Function, and Clinical Relevance, The Hague , Martinus Nijhoff, 1978, p. 112. 18 Strauss, H.G., Scheinman, M.M., La Barre, A., et al.: Review of the significance of drugs in the sick sinus syndrome. In F.I.M. Bonke, (ed.): The Sinus Node: Structure, Function, and Clinical Relevance, The Hague , Martinus Nijhoff, 1978, p, 103. 19 Jose, A.D.: Effect of combined sympathetic and parasympathetic blockade or heart rate and cardiac function in man. Am. J. Cardiol., 18: 476, 1966. 20 Jose, A.D., Collison, D.: The normal range and de terminants of the intrinsic heart rate in man. Cardiovasc. Res., 4: 160, 1970. 21 Jordan, J.L., Yamaguchi, I., Mandel, W.J.: Studies on the mechanism of sinus node dysfunction in the sick sinus syndrome. Circulation. 57: 217, 1978. 22 Mandel, W.J., Hayakawa, H., Danzig, R., et al.: Eval uation of sino-atrial node function in man by ov erdrive suppression. Circulalion, 44: 59, 1971. 23 Rosen, K.M., Loeb. H.S., Sinno, M.Z., et al.: Cardiac conduction in patients with symptomatic sinus node disease. Circulation, 43: 836, 1971. 24 Narula, O.S., Samet, P., Xavier, R.P.: Significance of sinus-node recovery time. Circulation, 45: 140, 1972. 25 Reiffel, J.A., Bigger, J.T., Jr., Griandina, E.G.V.: “Paradoxical” prolongation of sinus node recovery time after atropine in the sick sinus syndrome. Am. J. Cardiol., 36: 98, 1975. 26 Gang, E., Reiffel, J.A., Livelli, F.D., Jr., et al.: Sinus node recovery times following spontaneous ter mination of supraventricular tachycardia and fol lowing atrial overdrive pacing: A comparison. Am. Heart J., 105: 210, 1983. 27 Kulbertus, H.E., de Leval-Rutten, F., Casters, L.: Sinus node recovery time in elderly. Br. Heart J., 37: 420, 1975. 28 Chadda, K.D., Banka, U.S., Bodenheimer, M.M., et al.: Corrected sinus node recovery time: Experi mental, physiologic and pathologic determinants. Circulation 51: 797, 1975. 29 Bashaurt, T.: An unusual effect of atropine on ov erdrive suppression. Circulalion, 48: 911, 1973. 30 Benditt, D.G., Strauss, H.C., Scheinman, M.M., et al.: Analysis of secondary pauses following ter mination of rapid atrial pacing in man. Circula tion, 54: 436, 1976. 31 Jordan, JL., Mandel, W.J.: Disorders of sinus func tion. In Cardiac Arrhythmias: Their Mechanisms, Diagnosis, and Management. W.J. Mandel, (ed.), Philadelphia and Toronto , Lippincott, 1980, p. 107. 32 Pop, T., Fleischmann, D.: Measurement of sinus node recovery time after atrial pacing. In F.I.M. Bonke, (ed.): The Sinus Node: Structure, Function, and Clinical Relevance, The Hague , Martinus Nijhoff, 1978, p, 23. 33 Strauss, H.C., Bigger, J.T., Jr., Saroff, A.L., et al.: Electrophysiologic evaluation of sinus node func tion in patients with sinus node dysfunction. Cir culalion, 53: 763, 1976. 34 Scheinman, M.M., Strauss, H.C., Abbott, J.A.: Elec trophysiologic testing for patients with sinus node dysfunction. J. Electrocardiol., 12: 211, 1979. 35 Reiffel, J.A., Gang, E., Bigger, J.T., Jr., et al.: Sinus node recovery time related to paced cycle length in normals and patients with sinoatrial dysfunc tion. Am. Hearl J., 104: 746, 1982. 36 Delius, W., Wirtzfeld, A.: Significance of sinus node recovery time in sick sinus syndrome. In B. Luderitz, (ed.): Cardiac Pacing, Berlin , Springer, 1976, p. 25. 37 Strauss, H.C., Saroff, A.L., Bigger. J.T., Jr., et al.: Premature atrial stimulation as a key to the un derstanding of sinoatrial conduction in man: Pres entation of data and a critical review of the liter ature, Circulalion, 47: 86, 1973. 38 Narula, O.S., Shantha, N., Vasquez, M., et al.: A new method for measurement of sinoatrial con duction time, Circulation, 58: 706, 1978. 39 Cramer, M., Hariman, R.J., Boxer, R., and Hoffman, B.F.: Electrograms from the canine sinoatrial pacemaker recorded in vitro and in situ. Am. J. Cardiol., 42: 939, 1978. 40 Reiffel, J., Gang, E., Glicklich, J., et al.: The human sinus node electrogram: A transvenous catheter technique and comparison of directly measured and indirectly estimated sinoatrial conduction time in adults. Circulation. 62: 1324, 1980. 41 Hariman, R.J., Krongrad, E., Boxer, R., et al.: Meth ods for recording electrical activity in the sinoatrial node and automatic foci during cardiac catheterization in human suhjects. Am. J. Cardiol., 45: 775, 1980. 42 Dhingra, R.C, Amat-y-Leon, F., Wyndham, C. et al.: Clinical significance of prolonged sinoatrial conduction time. Circulation, 55: 8, 1977. 43 Bigger, J.T., Jr.: A simple, rapid method for the diagnosis of first-degree sinoatrial block in man. Am. Heart J., 87: 731, 1974. 44 Breithardt, G., Seipel, L., Loogen, F.: Sinus node recovery time and calculated sinoatrial conduction time in normal subjects and patients with sinus node dysfunction. Circulation, 56: 43, 1977. 45 Miller, H.C., Strauss. H.G.: Measurement of sinoa trial conduction time by premature atrial stimu lation in tbe rabbit. Circ. Res., 35: 935, 1974. 46 Bonke, F.I.M., Bouman, L.N., Schopman, F.J.G.: Ef fect of an early atrial premature beat on activity of the sinoatrial rhythm in the rabbit. Circ. Res., 24: 704, 1971. 47 Breilhardt, G., Seipel, L.: The effect of premature atrial depolarization on sinus node automaticity in man. Circulation, 53: 920, 1976. 48 Bigger, J.T., Jr., Reiffel, J.A.: Sick sinus syndrome. Ann. Rev. Med., 30: 91, 1979. 49 Reiffel, J.A., Gang, E., Livelli, F., Jr., et al.: Glinical and electropbysiologic characteristics of sinoatrial entrance block evaluated by direct sinus node electrography: Prevalence, relation to antegrade sinoa triai conduction time, and relevance to sinus node disease. Am. Heart J., 102: 1011, 1981. 50 Dhingra, R.G., Amat-Y-Leon, F., Wyndham, C, et al.: Electrophysiological effects of atropine on sinus node and atrium in patients with sinus node dys function. Am. J. Cardiol., 38: 848, 1976. 51 Strauss, H.G., Gilbert, M., Svenson, R.H., et al.: Electrophysiological effects of propranolol on sinus node function in patients with sinus node dys function. Circulation, 54: 452, 1976. 52 Strauss, H.G., Bigger, J.T., Jr., Saroff, A.L., et al.: Electrophysiologic evaluation of sinus node func tion in patients with sinus node dysfunction. Cir culation, 53: 763, 1976. 53 Kerr. C.R., Grant, A.O., Wenger, T.L., et al.: Sinus node dysfunction. Cardiol. Clin. 1: 187, 1983. 54 Gomes, J.A.G., Kang, P.S., El-Sherif, N.: The sinus node electrogram in patients with and without sick sinus syndrome: Techniques and correlation be tween directly measured and indirectly estimated sinoatrial conduction time. Circulation, 66: 864, 1982. 55 Reiffel, J.A., Gang, E., Livelli, F., et al.: Indirectly estimated sinoatrial conduction time by the atrial premature stimulus techniques: Patterns of error and the degree of associated inaccuracy as assessed hy direct sinus node electrography. Am. Heart J., 106: 459, 1983. 56 Asseman, P., Berzin, B., Desry. D., et al.: Persistent sinus node electrograms during abnormally pro longed post-pacing atrial pauses in sick sinus syn drome in bumans; sinoatrial block vs overdrive suppression. Circulation, 68: 33, 1983. 57 Goldreyer, B.N., Damato, A.N.: Sinoatrial node en trance block. Circulation, 44: 789, 1971. 58 Kerr. G.R., Prystowsky, E.N., Browning, D.J., et al.: Gbaracterization of refractoriness in the sinus node of the rabbit. Circ. Res., 47: 742, 1980. 59 Kerr, C.R., Strauss, H.G.: The measurement of sinus node refractoriness in man. Circulation, 68: 1231, 1983. Citing Literature Volume8, Issue2March 1985Pages 242-254 ReferencesRelatedInformation" @default.
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