FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034453470> ?p ?o ?g. }

• W2034453470 endingPage "263" @default.
• W2034453470 startingPage "256" @default.
• W2034453470 abstract "Coxsackievirus B5 (CVB5), a human enterovirus of the family Picornaviridae , is a frequent cause of acute and chronic human diseases. The pathogenesis of enteroviral infections is not completely understood, and the fate of the CVB5-infected cell has a pivotal role in this process. We have investigated the CVB5-induced apoptosis of HeLa cells and found that it happens by the intrinsic pathway by a mechanism dependent on the ubiquitin–proteasome system, associated with nuclear aggregation of p53. Striking redistribution of both SUMO and UBC9 was noted at 4 h post-infection, simultaneously with a reduction in the levels of the ubiquitin-ligase HDM2. Taken together, these results suggest that CVB5 infection of HeLa cells elicit the intrinsic pathway of apoptosis by MDM2 degradation and p53 activation, destabilizing protein sumoylation, by a mechanism that is dependent on a functional ubiquitin–proteasome system." @default.
• W2034453470 created "2016-06-24" @default.
• W2034453470 creator A5044523408 @default.
• W2034453470 creator A5045899915 @default.
• W2034453470 creator A5070023618 @default.
• W2034453470 date "2010-01-01" @default.
• W2034453470 modified "2023-10-17" @default.
• W2034453470 title "Coxsackievirus B5 induced apoptosis of HeLa cells: Effects on p53 and SUMO" @default.
• W2034453470 cites W1607777232 @default.
• W2034453470 cites W1975563698 @default.
• W2034453470 cites W1978154616 @default.
• W2034453470 cites W1979051583 @default.
• W2034453470 cites W1987951352 @default.
• W2034453470 cites W1992470503 @default.
• W2034453470 cites W1993170641 @default.
• W2034453470 cites W1999541802 @default.
• W2034453470 cites W2002115764 @default.
• W2034453470 cites W2007249806 @default.
• W2034453470 cites W2020942480 @default.
• W2034453470 cites W2031253712 @default.
• W2034453470 cites W2033447671 @default.
• W2034453470 cites W2037279384 @default.
• W2034453470 cites W2039382131 @default.
• W2034453470 cites W2039689821 @default.
• W2034453470 cites W2040938702 @default.
• W2034453470 cites W2045245022 @default.
• W2034453470 cites W2050297509 @default.
• W2034453470 cites W2055887339 @default.
• W2034453470 cites W2066632548 @default.
• W2034453470 cites W2071548370 @default.
• W2034453470 cites W2076673612 @default.
• W2034453470 cites W2080485991 @default.
• W2034453470 cites W2083711237 @default.
• W2034453470 cites W2084371769 @default.
• W2034453470 cites W2084970371 @default.
• W2034453470 cites W2126430714 @default.
• W2034453470 cites W2145523114 @default.
• W2034453470 cites W2150996850 @default.
• W2034453470 cites W2167482717 @default.
• W2034453470 cites W2169518072 @default.
• W2034453470 doi "https://doi.org/10.1016/j.virol.2009.10.005" @default.
• W2034453470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19906394" @default.
• W2034453470 hasPublicationYear "2010" @default.
• W2034453470 type Work @default.
• W2034453470 sameAs 2034453470 @default.
• W2034453470 citedByCount "16" @default.
• W2034453470 countsByYear W20344534702012 @default.
• W2034453470 countsByYear W20344534702014 @default.
• W2034453470 countsByYear W20344534702015 @default.
• W2034453470 countsByYear W20344534702016 @default.
• W2034453470 countsByYear W20344534702017 @default.
• W2034453470 countsByYear W20344534702018 @default.
• W2034453470 countsByYear W20344534702020 @default.
• W2034453470 countsByYear W20344534702021 @default.
• W2034453470 countsByYear W20344534702022 @default.
• W2034453470 countsByYear W20344534702023 @default.
• W2034453470 crossrefType "journal-article" @default.
• W2034453470 hasAuthorship W2034453470A5044523408 @default.
• W2034453470 hasAuthorship W2034453470A5045899915 @default.
• W2034453470 hasAuthorship W2034453470A5070023618 @default.
• W2034453470 hasBestOaLocation W20344534701 @default.
• W2034453470 hasConcept C104317684 @default.
• W2034453470 hasConcept C134459356 @default.
• W2034453470 hasConcept C159047783 @default.
• W2034453470 hasConcept C171350616 @default.
• W2034453470 hasConcept C190283241 @default.
• W2034453470 hasConcept C2522874641 @default.
• W2034453470 hasConcept C25602115 @default.
• W2034453470 hasConcept C27740335 @default.
• W2034453470 hasConcept C2776192174 @default.
• W2034453470 hasConcept C2777366897 @default.
• W2034453470 hasConcept C2777888124 @default.
• W2034453470 hasConcept C2779120600 @default.
• W2034453470 hasConcept C54355233 @default.
• W2034453470 hasConcept C81885089 @default.
• W2034453470 hasConcept C86803240 @default.
• W2034453470 hasConcept C95444343 @default.
• W2034453470 hasConceptScore W2034453470C104317684 @default.
• W2034453470 hasConceptScore W2034453470C134459356 @default.
• W2034453470 hasConceptScore W2034453470C159047783 @default.
• W2034453470 hasConceptScore W2034453470C171350616 @default.
• W2034453470 hasConceptScore W2034453470C190283241 @default.
• W2034453470 hasConceptScore W2034453470C2522874641 @default.
• W2034453470 hasConceptScore W2034453470C25602115 @default.
• W2034453470 hasConceptScore W2034453470C27740335 @default.
• W2034453470 hasConceptScore W2034453470C2776192174 @default.
• W2034453470 hasConceptScore W2034453470C2777366897 @default.
• W2034453470 hasConceptScore W2034453470C2777888124 @default.
• W2034453470 hasConceptScore W2034453470C2779120600 @default.
• W2034453470 hasConceptScore W2034453470C54355233 @default.
• W2034453470 hasConceptScore W2034453470C81885089 @default.
• W2034453470 hasConceptScore W2034453470C86803240 @default.
• W2034453470 hasConceptScore W2034453470C95444343 @default.
• W2034453470 hasFunder F4320320997 @default.
• W2034453470 hasIssue "2" @default.
• W2034453470 hasLocation W20344534701 @default.
• W2034453470 hasLocation W20344534702 @default.
• W2034453470 hasLocation W20344534703 @default.

• next