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- W2034456488 abstract "Die elektrostatische Wechselwirkung ist entscheidend bei der Bindung von Aminoglycosid-Antibiotica an RNA. Dies ergab der Austausch von OH- gegen NH2-Gruppen, z.B. in Kanamycin A 1. Das Derivat 2 inhibiert ein Hammerhead-Ribozym viel starker als 1. Es wird vorgeschlagen, das die raumliche Anordnung der positiven Ladungen die Bindungsstarke der Aminoglycoside bestimmt." @default.
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- W2034456488 date "1998-01-16" @default.
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- W2034456488 title "RNA‐Aminoglycosid‐Wechselwirkungen: Design und Synthese von „Amino‐aminoglycosiden”︁ und deren Bindung an RNA" @default.
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- W2034456488 doi "https://doi.org/10.1002/(sici)1521-3757(19980116)110:1/2<117::aid-ange117>3.0.co;2-#" @default.
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