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- W2034457057 abstract "Vitronectin (complement S-protein), a plasma and tissue glycoprotein of 75 kDa, shares the amino-terminal somatomedin B domain with the membrane glycoprotein PC1 of plasma cells and several hemopexin-type repeats with hemopexin and the non-catalytic carboxy-terminal domain of collagenases. It serves as a ligand for certain integrin receptors, binds to distinct members of the serpin family and inhibits the pore-forming cytolytic reaction of the terminal complement pathway. Computer-assisted data base searches revealed the presence of a single somatomedin B domain in the recently cloned placental protein 11, and four hemopexin-type repeats in the cytosolic plant protein PA2, the major albumin of pea seeds, whose function is unknown. Our finding shows that hemopexin-type repeats are present in extracellular as well as in cytosolic proteins and most likely originated before the divergence of the animal and plant kindoms." @default.
- W2034457057 created "2016-06-24" @default.
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- W2034457057 date "1991-05-01" @default.
- W2034457057 modified "2023-09-23" @default.
- W2034457057 title "Homology of placental protein 11 and pea seed albumin 2 with vitronectin" @default.
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- W2034457057 doi "https://doi.org/10.1016/0006-291x(91)90381-g" @default.
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