FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034458377> ?p ?o ?g. }

• W2034458377 endingPage "4931" @default.
• W2034458377 startingPage "4927" @default.
• W2034458377 abstract "The function of a TATA element in RNA polymerase (EC 2.7.7.6) III transcription of a naturally TATA-containing U6 snRNA gene and a naturally TATA-less tRNA gene was probed by transcription and Ty3 transposition analyses. Deletion of the TATA box from a U6 minigene did not abolish transcription and Ty3 integration but changed the positions of initiation and insertion. Insertion of the U6 TATA box at three positions upstream of the TATA-less SUP2 tRNA(Tyr) gene resulted in novel transcription initiation and Ty3 integration patterns that depended upon position of the insertion. Nevertheless, the predominant tRNA gene initiation sites were not affected by insertion of the TATA sequence and remained at a fixed distance from the internal box A promoter element. Insertions of the TATA box upstream of a SUP2 box A mutant affected the level of transcription and restricted the use of upstream start sites, but they neither enhanced the use of TATA-dependent initiation sites nor restored expression to the level of the wild-type gene. We conclude that (i) the U6 TATA box is essential in vivo for correct initiation but not for transcription, (ii) a TATA box does not compensate for a weak box A sequence and so cannot perform equivalently, and (iii) the TATA-binding protein, and probably components of transcription factor IIIB, are present on the target at the time of Ty3 integration." @default.
• W2034458377 created "2016-06-24" @default.
• W2034458377 creator A5029367275 @default.
• W2034458377 creator A5075351356 @default.
• W2034458377 date "1993-06-01" @default.
• W2034458377 modified "2023-10-17" @default.
• W2034458377 title "Sites of RNA polymerase III transcription initiation and Ty3 integration at the U6 gene are positioned by the TATA box." @default.
• W2034458377 cites W1500459843 @default.
• W2034458377 cites W1517442337 @default.
• W2034458377 cites W1775710116 @default.
• W2034458377 cites W1950038354 @default.
• W2034458377 cites W1973381207 @default.
• W2034458377 cites W1974850260 @default.
• W2034458377 cites W1999738251 @default.
• W2034458377 cites W2006624258 @default.
• W2034458377 cites W2006630070 @default.
• W2034458377 cites W2013786607 @default.
• W2034458377 cites W2020830418 @default.
• W2034458377 cites W2028260685 @default.
• W2034458377 cites W2042099787 @default.
• W2034458377 cites W2051082289 @default.
• W2034458377 cites W2060137850 @default.
• W2034458377 cites W2074268165 @default.
• W2034458377 cites W2078366770 @default.
• W2034458377 cites W2089971545 @default.
• W2034458377 cites W2093520735 @default.
• W2034458377 cites W2103808553 @default.
• W2034458377 cites W2108483626 @default.
• W2034458377 cites W2116292068 @default.
• W2034458377 cites W2138538616 @default.
• W2034458377 cites W2156071334 @default.
• W2034458377 cites W2156102046 @default.
• W2034458377 doi "https://doi.org/10.1073/pnas.90.11.4927" @default.
• W2034458377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/46626" @default.
• W2034458377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8389458" @default.
• W2034458377 hasPublicationYear "1993" @default.
• W2034458377 type Work @default.
• W2034458377 sameAs 2034458377 @default.
• W2034458377 citedByCount "40" @default.
• W2034458377 countsByYear W20344583772012 @default.
• W2034458377 countsByYear W20344583772013 @default.
• W2034458377 countsByYear W20344583772015 @default.
• W2034458377 countsByYear W20344583772018 @default.
• W2034458377 countsByYear W20344583772019 @default.
• W2034458377 countsByYear W20344583772021 @default.
• W2034458377 countsByYear W20344583772022 @default.
• W2034458377 crossrefType "journal-article" @default.
• W2034458377 hasAuthorship W2034458377A5029367275 @default.
• W2034458377 hasAuthorship W2034458377A5075351356 @default.
• W2034458377 hasBestOaLocation W20344583771 @default.
• W2034458377 hasConcept C101762097 @default.
• W2034458377 hasConcept C104317684 @default.
• W2034458377 hasConcept C138885662 @default.
• W2034458377 hasConcept C150194340 @default.
• W2034458377 hasConcept C153911025 @default.
• W2034458377 hasConcept C172768829 @default.
• W2034458377 hasConcept C179716448 @default.
• W2034458377 hasConcept C179926584 @default.
• W2034458377 hasConcept C2776449523 @default.
• W2034458377 hasConcept C2909959438 @default.
• W2034458377 hasConcept C41895202 @default.
• W2034458377 hasConcept C44498088 @default.
• W2034458377 hasConcept C54355233 @default.
• W2034458377 hasConcept C64350747 @default.
• W2034458377 hasConcept C65888428 @default.
• W2034458377 hasConcept C67705224 @default.
• W2034458377 hasConcept C70916841 @default.
• W2034458377 hasConcept C86803240 @default.
• W2034458377 hasConceptScore W2034458377C101762097 @default.
• W2034458377 hasConceptScore W2034458377C104317684 @default.
• W2034458377 hasConceptScore W2034458377C138885662 @default.
• W2034458377 hasConceptScore W2034458377C150194340 @default.
• W2034458377 hasConceptScore W2034458377C153911025 @default.
• W2034458377 hasConceptScore W2034458377C172768829 @default.
• W2034458377 hasConceptScore W2034458377C179716448 @default.
• W2034458377 hasConceptScore W2034458377C179926584 @default.
• W2034458377 hasConceptScore W2034458377C2776449523 @default.
• W2034458377 hasConceptScore W2034458377C2909959438 @default.
• W2034458377 hasConceptScore W2034458377C41895202 @default.
• W2034458377 hasConceptScore W2034458377C44498088 @default.
• W2034458377 hasConceptScore W2034458377C54355233 @default.
• W2034458377 hasConceptScore W2034458377C64350747 @default.
• W2034458377 hasConceptScore W2034458377C65888428 @default.
• W2034458377 hasConceptScore W2034458377C67705224 @default.
• W2034458377 hasConceptScore W2034458377C70916841 @default.
• W2034458377 hasConceptScore W2034458377C86803240 @default.
• W2034458377 hasIssue "11" @default.
• W2034458377 hasLocation W20344583771 @default.
• W2034458377 hasLocation W20344583772 @default.
• W2034458377 hasLocation W20344583773 @default.
• W2034458377 hasLocation W20344583774 @default.
• W2034458377 hasLocation W20344583775 @default.
• W2034458377 hasOpenAccess W2034458377 @default.
• W2034458377 hasPrimaryLocation W20344583771 @default.
• W2034458377 hasRelatedWork W1871847816 @default.
• W2034458377 hasRelatedWork W1982417353 @default.
• W2034458377 hasRelatedWork W1987270520 @default.
• W2034458377 hasRelatedWork W2027281272 @default.

• next