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- W2034460445 abstract "Timefurone (1), a methyl thioether analogue of khellin (2), was labeled with tritium at the C-2 position and with carbon-14 at the C-5 position for conducting in vivo biotransformation studies with 1. Tritium labeled 1 was prepared by lithiating and tritiating a silyllated derivative of khellinone (3) at C-2, followed by converting the labeled khellinone into 1. Carbon-14 labeled 1 was obtained by first dismantling the pyrone ring of khellin, followed by reconstruction of the ring with incorporation of carbon-14 into the carbonyl position." @default.
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- W2034460445 date "1985-12-01" @default.
- W2034460445 modified "2023-09-25" @default.
- W2034460445 title "Synthesis of tritium and carbon-14 labeled timefurone" @default.
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- W2034460445 doi "https://doi.org/10.1002/jlcr.2580221209" @default.
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