FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034504405> ?p ?o ?g. }

• W2034504405 endingPage "756" @default.
• W2034504405 startingPage "756" @default.
• W2034504405 abstract "Acute epididymitis represents a common medical condition in the urological outpatient clinic. Mostly, epididymitis is caused by bacterial ascent through the urogenital tract, with pathogens originating either from sexually transmitted diseases or urinary tract infections. Although conservative antimicrobial therapy is possible in the majority of patients and is usually sufficient to eradicate the pathogen, studies have shown persistent oligozoospermia and azoospermia in up to 40% of these patients. Animal models of epididymitis are created to delineate the underlying reasons for this observation and the additional impairment of sperm function that is often associated with the disease. Accumulated data provide evidence of a differential expression of immune cells, immunoregulatory genes and pathogen-sensing molecules along the length of the epididymal duct. The evidence suggests that a tolerogenic environment exists in the caput epididymidis, but that inflammatory responses are most intense toward the cauda epididymidis. This is consistent with the need to provide protection for the neo-antigens of spermatozoa emerging from the testis, without compromising the ability to respond to ascending infections. However, severe inflammatory responses, particularly in the cauda, may lead to collateral damage to the structure and function of the epididymis. Convergence of the clinical observations with appropriate animal studies should lead to better understanding of the immunological environment throughout the epididymis, the parameters underlying susceptibility to epididymitis, and to therapeutic approaches that can mitigate epididymal damage and subsequent fertility problems." @default.
• W2034504405 created "2016-06-24" @default.
• W2034504405 creator A5016633036 @default.
• W2034504405 creator A5022826774 @default.
• W2034504405 creator A5045353162 @default.
• W2034504405 creator A5082258057 @default.
• W2034504405 date "2015-01-01" @default.
• W2034504405 modified "2023-10-10" @default.
• W2034504405 title "Epididymitis: revelations at the convergence of clinical and basic sciences" @default.
• W2034504405 cites W110071969 @default.
• W2034504405 cites W1535510497 @default.
• W2034504405 cites W1561028553 @default.
• W2034504405 cites W1591275079 @default.
• W2034504405 cites W186960012 @default.
• W2034504405 cites W192352086 @default.
• W2034504405 cites W196409618 @default.
• W2034504405 cites W1964580044 @default.
• W2034504405 cites W1965927403 @default.
• W2034504405 cites W1967722062 @default.
• W2034504405 cites W1974199654 @default.
• W2034504405 cites W1980206198 @default.
• W2034504405 cites W1982001600 @default.
• W2034504405 cites W1982377655 @default.
• W2034504405 cites W1987575651 @default.
• W2034504405 cites W1995744610 @default.
• W2034504405 cites W1996941752 @default.
• W2034504405 cites W2006611096 @default.
• W2034504405 cites W2007316487 @default.
• W2034504405 cites W2014373883 @default.
• W2034504405 cites W2015362266 @default.
• W2034504405 cites W2016916101 @default.
• W2034504405 cites W2018758430 @default.
• W2034504405 cites W2019489688 @default.
• W2034504405 cites W2020658268 @default.
• W2034504405 cites W2022066081 @default.
• W2034504405 cites W2023484935 @default.
• W2034504405 cites W2027881441 @default.
• W2034504405 cites W2032222569 @default.
• W2034504405 cites W2035759880 @default.
• W2034504405 cites W2036159805 @default.
• W2034504405 cites W2038996752 @default.
• W2034504405 cites W2040317651 @default.
• W2034504405 cites W2044784792 @default.
• W2034504405 cites W2045384882 @default.
• W2034504405 cites W2047691516 @default.
• W2034504405 cites W2049821805 @default.
• W2034504405 cites W2053313508 @default.
• W2034504405 cites W2053559630 @default.
• W2034504405 cites W2058353165 @default.
• W2034504405 cites W2059638656 @default.
• W2034504405 cites W2060973188 @default.
• W2034504405 cites W2063919732 @default.
• W2034504405 cites W2065769963 @default.
• W2034504405 cites W2068145757 @default.
• W2034504405 cites W2073378866 @default.
• W2034504405 cites W2075656676 @default.
• W2034504405 cites W2086364595 @default.
• W2034504405 cites W2087026777 @default.
• W2034504405 cites W2089664874 @default.
• W2034504405 cites W2091571972 @default.
• W2034504405 cites W2093028882 @default.
• W2034504405 cites W2094377191 @default.
• W2034504405 cites W2095886784 @default.
• W2034504405 cites W2103892037 @default.
• W2034504405 cites W2104144767 @default.
• W2034504405 cites W2106830125 @default.
• W2034504405 cites W2110276365 @default.
• W2034504405 cites W2113480441 @default.
• W2034504405 cites W2115744257 @default.
• W2034504405 cites W2115943880 @default.
• W2034504405 cites W2121560701 @default.
• W2034504405 cites W2123494997 @default.
• W2034504405 cites W2124631560 @default.
• W2034504405 cites W2124876474 @default.
• W2034504405 cites W2127856646 @default.
• W2034504405 cites W2136658112 @default.
• W2034504405 cites W2137076688 @default.
• W2034504405 cites W2137150893 @default.
• W2034504405 cites W2141582368 @default.
• W2034504405 cites W2142521537 @default.
• W2034504405 cites W2143095603 @default.
• W2034504405 cites W2148836159 @default.
• W2034504405 cites W2150629919 @default.
• W2034504405 cites W2156051831 @default.
• W2034504405 cites W2159649939 @default.
• W2034504405 cites W2163277254 @default.
• W2034504405 cites W2204132273 @default.
• W2034504405 cites W2228209615 @default.
• W2034504405 cites W2278899719 @default.
• W2034504405 cites W2296017442 @default.
• W2034504405 cites W2314037103 @default.
• W2034504405 cites W2318215418 @default.
• W2034504405 cites W2395903537 @default.
• W2034504405 cites W2403954327 @default.
• W2034504405 cites W2405192317 @default.
• W2034504405 cites W2416908663 @default.
• W2034504405 cites W2419007840 @default.
• W2034504405 cites W2419189113 @default.

• next