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- W2034508045 abstract "Psychiatric disorders place a large burden not only on affected individuals and their families but also on societies and health services. Current treatment is only effective in a proportion of the patients, so considerable effort has been put into the development of new medications. The susceptibility to all major psychiatric disorders is, at least in part, genetic. Knowledge of the genes that underlie this susceptibility may lead to the identification of new drug targets and the development of more effective treatments. Therefore, numerous genetic studies in search for the genes involved in psychiatric disorders have been performed. Although results of both linkage and association studies have been inconsistent, several promising gene regions and candidate genes have been identified recently. In this article, we will review the strategies that proved to be successful in detecting genes for psychiatric disorders and we will provide some recommendations to increase the probability of detecting susceptibility genes in genetic studies of different designs." @default.
- W2034508045 created "2016-06-24" @default.
- W2034508045 creator A5039693078 @default.
- W2034508045 creator A5057989264 @default.
- W2034508045 date "2006-06-01" @default.
- W2034508045 modified "2023-09-24" @default.
- W2034508045 title "Genetic analysis of psychiatric disorders in humans" @default.
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- W2034508045 doi "https://doi.org/10.1111/j.1601-183x.2006.00223.x" @default.
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