FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034549354> ?p ?o ?g. }

• W2034549354 endingPage "505" @default.
• W2034549354 startingPage "499" @default.
• W2034549354 abstract "The anatomy of the epidermis, dermis and subcutaneous tissues of the nail apparatus is distinct from that of non-appendageal skin. Apart from the demonstration of the longitudinal configuration of the dermal-epidermal junction of the nail bed, there have been no studies of the composition of the basement membrane zone of the nail apparatus. We obtained three human accessory digits, including one thumb, all of which had been amputated for cosmetic reasons, and were without known pathology. Specimens were stained with a battery of monoclonal and polyclonal antibodies which target normal basement membrane zone antigens, and studied by indirect immunoflourescence. This study demonstrated that the four distinct regions of the nail, namely the proximal nail fold, the nail matrix, the nail bed and the hyponychium expressed all the target antigens found in the normal non-appendageal basement membrane. In particular, there was normal expression of the epidermal-associated antigens, the 220-and 180-kDa bullous pemphigoid antigens, and the α6β4 integrin. There was also normal expression of the lamina lucida antigens LH39, GB3 and laminin. It is of interest that the dermal-associated components, namely the 285-kDa linear IgA antigen, the extracellular matrix glycoproteins chondroitin sulphate, type VII collagen and its closely associated proteins, and the poorly characterized antigen for LH24 and LH39 were all normally expressed.Fibronectin, which is not a normal basement membrane zone component, was diffusely expressed in the extracellular matrix, but did not accentuate the basement membrane zone. LHF2, an antibody raised against tenascin, which shows weak positive staining at the tips of dermal papillae in normal skin (unpublished data) diffusely stained the extracellular matrix and the tips of the dermal papillae of the nail matrix and hyponychium, but did not stain the basement membrane of the nail bed. These findings show that despite the numerous distinct features of epidermis, dermis and subcutis of the nail apparatus, the basement membrane zone has virtually identical antigen expression to that of the dermal-epidermal junction elsewhere. The difference in LHF2 expression in the nail bed most likely reflects the different shape of the nail bed basement membrane, which is arranged in longitudinal folds." @default.
• W2034549354 created "2016-06-24" @default.
• W2034549354 creator A5015713295 @default.
• W2034549354 creator A5033907428 @default.
• W2034549354 creator A5035044854 @default.
• W2034549354 creator A5047719176 @default.
• W2034549354 date "2006-07-29" @default.
• W2034549354 modified "2023-10-16" @default.
• W2034549354 title "The basement membrane zone of the nail" @default.
• W2034549354 cites W1968734623 @default.
• W2034549354 cites W1998061526 @default.
• W2034549354 cites W2001533176 @default.
• W2034549354 cites W2002747020 @default.
• W2034549354 cites W2019984225 @default.
• W2034549354 cites W2083500716 @default.
• W2034549354 cites W2085129359 @default.
• W2034549354 cites W2120163316 @default.
• W2034549354 cites W2338193938 @default.
• W2034549354 doi "https://doi.org/10.1111/j.1365-2133.1994.tb08550.x" @default.
• W2034549354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7524609" @default.
• W2034549354 hasPublicationYear "2006" @default.
• W2034549354 type Work @default.
• W2034549354 sameAs 2034549354 @default.
• W2034549354 citedByCount "42" @default.
• W2034549354 countsByYear W20345493542012 @default.
• W2034549354 countsByYear W20345493542013 @default.
• W2034549354 countsByYear W20345493542015 @default.
• W2034549354 countsByYear W20345493542016 @default.
• W2034549354 countsByYear W20345493542017 @default.
• W2034549354 countsByYear W20345493542018 @default.
• W2034549354 countsByYear W20345493542019 @default.
• W2034549354 countsByYear W20345493542020 @default.
• W2034549354 countsByYear W20345493542021 @default.
• W2034549354 countsByYear W20345493542022 @default.
• W2034549354 countsByYear W20345493542023 @default.
• W2034549354 crossrefType "journal-article" @default.
• W2034549354 hasAuthorship W2034549354A5015713295 @default.
• W2034549354 hasAuthorship W2034549354A5033907428 @default.
• W2034549354 hasAuthorship W2034549354A5035044854 @default.
• W2034549354 hasAuthorship W2034549354A5047719176 @default.
• W2034549354 hasConcept C105702510 @default.
• W2034549354 hasConcept C142724271 @default.
• W2034549354 hasConcept C147483822 @default.
• W2034549354 hasConcept C153911025 @default.
• W2034549354 hasConcept C159654299 @default.
• W2034549354 hasConcept C185592680 @default.
• W2034549354 hasConcept C189165786 @default.
• W2034549354 hasConcept C191897082 @default.
• W2034549354 hasConcept C192562407 @default.
• W2034549354 hasConcept C203014093 @default.
• W2034549354 hasConcept C2776193487 @default.
• W2034549354 hasConcept C2776745646 @default.
• W2034549354 hasConcept C2777107211 @default.
• W2034549354 hasConcept C2777624698 @default.
• W2034549354 hasConcept C2777852167 @default.
• W2034549354 hasConcept C2778169587 @default.
• W2034549354 hasConcept C2779252107 @default.
• W2034549354 hasConcept C2779814568 @default.
• W2034549354 hasConcept C71924100 @default.
• W2034549354 hasConcept C86492073 @default.
• W2034549354 hasConcept C86803240 @default.
• W2034549354 hasConcept C95444343 @default.
• W2034549354 hasConceptScore W2034549354C105702510 @default.
• W2034549354 hasConceptScore W2034549354C142724271 @default.
• W2034549354 hasConceptScore W2034549354C147483822 @default.
• W2034549354 hasConceptScore W2034549354C153911025 @default.
• W2034549354 hasConceptScore W2034549354C159654299 @default.
• W2034549354 hasConceptScore W2034549354C185592680 @default.
• W2034549354 hasConceptScore W2034549354C189165786 @default.
• W2034549354 hasConceptScore W2034549354C191897082 @default.
• W2034549354 hasConceptScore W2034549354C192562407 @default.
• W2034549354 hasConceptScore W2034549354C203014093 @default.
• W2034549354 hasConceptScore W2034549354C2776193487 @default.
• W2034549354 hasConceptScore W2034549354C2776745646 @default.
• W2034549354 hasConceptScore W2034549354C2777107211 @default.
• W2034549354 hasConceptScore W2034549354C2777624698 @default.
• W2034549354 hasConceptScore W2034549354C2777852167 @default.
• W2034549354 hasConceptScore W2034549354C2778169587 @default.
• W2034549354 hasConceptScore W2034549354C2779252107 @default.
• W2034549354 hasConceptScore W2034549354C2779814568 @default.
• W2034549354 hasConceptScore W2034549354C71924100 @default.
• W2034549354 hasConceptScore W2034549354C86492073 @default.
• W2034549354 hasConceptScore W2034549354C86803240 @default.
• W2034549354 hasConceptScore W2034549354C95444343 @default.
• W2034549354 hasIssue "4" @default.
• W2034549354 hasLocation W20345493541 @default.
• W2034549354 hasLocation W20345493542 @default.
• W2034549354 hasOpenAccess W2034549354 @default.
• W2034549354 hasPrimaryLocation W20345493541 @default.
• W2034549354 hasRelatedWork W1935625957 @default.
• W2034549354 hasRelatedWork W1966940470 @default.
• W2034549354 hasRelatedWork W2013736587 @default.
• W2034549354 hasRelatedWork W2025195149 @default.
• W2034549354 hasRelatedWork W2049946344 @default.
• W2034549354 hasRelatedWork W2167249168 @default.
• W2034549354 hasRelatedWork W2363089186 @default.
• W2034549354 hasRelatedWork W2380145641 @default.
• W2034549354 hasRelatedWork W2418764233 @default.

• next