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• W2034558558 endingPage "034101" @default.
• W2034558558 startingPage "034101" @default.
• W2034558558 abstract "The presence of non-autologous major histocompatibility complex class I (MHC-I) molecules on the surface of the grafted cells is one of the main reasons for their rejection in non-syngeneic hosts. We present a straightforward strategy to decrease the presence of MHC-I by shRNA inhibition of beta-2-microglobulin (B2M), a conservative light chain of MHC-I, on the surface of two main cell types that are used to engineer heart tissue constructs." @default.
• W2034558558 created "2016-06-24" @default.
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• W2034558558 date "2015-03-16" @default.
• W2034558558 modified "2023-09-25" @default.
• W2034558558 title "Downregulation of beta-microglobulin to diminish T-lymphocyte lysis of non-syngeneic cell sources of engineered heart tissue constructs" @default.
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• W2034558558 doi "https://doi.org/10.1088/1748-6041/10/3/034101" @default.
• W2034558558 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8083821" @default.
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