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• W2034602665 abstract "T lymphocytes are major contributors to post-ischemic neuroinflammation following ischemic stroke. However, the mode of postischemic T cell activation remains a controversial issue. Therefore, this study aimed to directly investigate antigen-dependent clonal T cell expansion after experimental brain ischemia using spectratype/immunoscope analysis. We detected clonal T cell expansion in ischemic brains and to a lesser extent in secondary lymphatic organs and characterized its time course. This is the first study presenting direct evidence of clonal T cell expansion after stroke - however, with delayed kinetics that make antigen-dependent mechanisms unlikely in acute post-ischemic neuroinflammation." @default.
• W2034602665 created "2016-06-24" @default.
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• W2034602665 date "2013-04-01" @default.
• W2034602665 modified "2023-10-02" @default.
• W2034602665 title "Spectratype analysis of clonal T cell expansion in murine experimental stroke" @default.
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• W2034602665 doi "https://doi.org/10.1016/j.jneuroim.2013.01.013" @default.
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