FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034607725> ?p ?o ?g. }

• W2034607725 endingPage "633" @default.
• W2034607725 startingPage "628" @default.
• W2034607725 abstract "Objectives. The purpose of this study was to elucidate whether the effectiveness of long-term beta-blocker therapy could be predicted before this therapy is started. Background. Long-term beta-blocker therapy has recently been reported to provide a favorable effect in treatment of congestive heart failure due to dilated cardiomyopathy. Methods. Several measurements including histologie variables before administration of metoprolo'. were retrospectively compared among 18 good responders (showing improvement of at least one New York Heart Association functional class or an increase in ejection fraction ≥0.10 12 months after drug administration) and 12 poor responders without such improvement. Results. Although there were no significant differences between the two groups in age, gender, functional class, heart rate, blood pressure, pulmonary capillary wedge pressure, cardiac index, left ventricular end-diastolic dimension and ejection fraction, percent fibrosis estimated by the point-counting method in endomyocardial biopsy specimens was significantly lower in good than in poor responders (7.6 ± 5.7 vs. 14.2 ± 9.7%, p < 0.05). Moreover, when the types of fibrosis were classified as interfascicular and intercellular by the dominance of counted points, there were 13 cases of interfascicular fibrosis and 5 cases of intercellular fibrosis in good responders and 1 case of interfascicular fibrosis and 11 cases of intercellular fibrosis in poor responders (p < 0.001, sensitivity 72%, specificity 91%, predictive accuracy 80%). These results suggest that improvement with long-term beta-blocker therapy may be more likely to occur in patients with less myocardial fibrosis, with interfascicular fibrosis the dominant type. Conclusions. The extent and type of fibrosis may be important factors in the prediction of the effectiveness of long-term betablocker therapy for dilated cardiomyopathy." @default.
• W2034607725 created "2016-06-24" @default.
• W2034607725 creator A5007206953 @default.
• W2034607725 creator A5015510633 @default.
• W2034607725 creator A5036390449 @default.
• W2034607725 creator A5043018639 @default.
• W2034607725 creator A5058884801 @default.
• W2034607725 creator A5065852130 @default.
• W2034607725 creator A5067949853 @default.
• W2034607725 creator A5071255742 @default.
• W2034607725 creator A5074487370 @default.
• W2034607725 creator A5078668392 @default.
• W2034607725 creator A5087013753 @default.
• W2034607725 date "1993-03-01" @default.
• W2034607725 modified "2023-10-06" @default.
• W2034607725 title "Which subgroup of patients with dilated cardiomyopathy would benefit from long-term beta-blocker therapy? A histologic viewpoint" @default.
• W2034607725 cites W1967340614 @default.
• W2034607725 cites W1981850993 @default.
• W2034607725 cites W1986344454 @default.
• W2034607725 cites W2001396507 @default.
• W2034607725 cites W2030742938 @default.
• W2034607725 cites W2039805827 @default.
• W2034607725 cites W2044204833 @default.
• W2034607725 cites W2045653700 @default.
• W2034607725 cites W2053829803 @default.
• W2034607725 cites W2054894807 @default.
• W2034607725 cites W2059843163 @default.
• W2034607725 cites W2062304838 @default.
• W2034607725 cites W2066920501 @default.
• W2034607725 cites W2071833353 @default.
• W2034607725 cites W2085788358 @default.
• W2034607725 cites W2095634382 @default.
• W2034607725 cites W2114758077 @default.
• W2034607725 cites W2119137159 @default.
• W2034607725 cites W2149550288 @default.
• W2034607725 cites W2163824552 @default.
• W2034607725 cites W2338638760 @default.
• W2034607725 cites W2416060197 @default.
• W2034607725 cites W4253544319 @default.
• W2034607725 doi "https://doi.org/10.1016/0735-1097(93)90094-h" @default.
• W2034607725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8094721" @default.
• W2034607725 hasPublicationYear "1993" @default.
• W2034607725 type Work @default.
• W2034607725 sameAs 2034607725 @default.
• W2034607725 citedByCount "83" @default.
• W2034607725 countsByYear W20346077252012 @default.
• W2034607725 countsByYear W20346077252013 @default.
• W2034607725 countsByYear W20346077252014 @default.
• W2034607725 countsByYear W20346077252015 @default.
• W2034607725 countsByYear W20346077252016 @default.
• W2034607725 countsByYear W20346077252017 @default.
• W2034607725 countsByYear W20346077252018 @default.
• W2034607725 countsByYear W20346077252019 @default.
• W2034607725 countsByYear W20346077252020 @default.
• W2034607725 countsByYear W20346077252021 @default.
• W2034607725 countsByYear W20346077252023 @default.
• W2034607725 crossrefType "journal-article" @default.
• W2034607725 hasAuthorship W2034607725A5007206953 @default.
• W2034607725 hasAuthorship W2034607725A5015510633 @default.
• W2034607725 hasAuthorship W2034607725A5036390449 @default.
• W2034607725 hasAuthorship W2034607725A5043018639 @default.
• W2034607725 hasAuthorship W2034607725A5058884801 @default.
• W2034607725 hasAuthorship W2034607725A5065852130 @default.
• W2034607725 hasAuthorship W2034607725A5067949853 @default.
• W2034607725 hasAuthorship W2034607725A5071255742 @default.
• W2034607725 hasAuthorship W2034607725A5074487370 @default.
• W2034607725 hasAuthorship W2034607725A5078668392 @default.
• W2034607725 hasAuthorship W2034607725A5087013753 @default.
• W2034607725 hasBestOaLocation W20346077251 @default.
• W2034607725 hasConcept C126322002 @default.
• W2034607725 hasConcept C146556889 @default.
• W2034607725 hasConcept C164705383 @default.
• W2034607725 hasConcept C2776383484 @default.
• W2034607725 hasConcept C2778198053 @default.
• W2034607725 hasConcept C2778797674 @default.
• W2034607725 hasConcept C2780559512 @default.
• W2034607725 hasConcept C3018763269 @default.
• W2034607725 hasConcept C57900726 @default.
• W2034607725 hasConcept C71924100 @default.
• W2034607725 hasConcept C78085059 @default.
• W2034607725 hasConcept C84393581 @default.
• W2034607725 hasConceptScore W2034607725C126322002 @default.
• W2034607725 hasConceptScore W2034607725C146556889 @default.
• W2034607725 hasConceptScore W2034607725C164705383 @default.
• W2034607725 hasConceptScore W2034607725C2776383484 @default.
• W2034607725 hasConceptScore W2034607725C2778198053 @default.
• W2034607725 hasConceptScore W2034607725C2778797674 @default.
• W2034607725 hasConceptScore W2034607725C2780559512 @default.
• W2034607725 hasConceptScore W2034607725C3018763269 @default.
• W2034607725 hasConceptScore W2034607725C57900726 @default.
• W2034607725 hasConceptScore W2034607725C71924100 @default.
• W2034607725 hasConceptScore W2034607725C78085059 @default.
• W2034607725 hasConceptScore W2034607725C84393581 @default.
• W2034607725 hasIssue "3" @default.
• W2034607725 hasLocation W20346077251 @default.
• W2034607725 hasLocation W20346077252 @default.
• W2034607725 hasOpenAccess W2034607725 @default.
• W2034607725 hasPrimaryLocation W20346077251 @default.

• next