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- W2034619091 abstract "Abstract Cryosurgical destruction of a functioning islet‐cell tumor was performed in hamsters. The mean blood sugar in tumor‐bearing animals before freezing was 67 mg per 100 ml. Four hours after tumor destruction it was 137 mg per 100 ml, and by 24 hours after treatment it was 110 mg per 100 ml. Respective mean plasma insulin values were 95 μU/ml, 33μU/ml, and 55 μU/ml, the normal range being 22 to 56 μU/ml. Blood sugar and plasma insulin levels were similarly affected after treatment in both cured animals and in those which later developed tumor recurrence or metastases. However, after the appearance of recurrent tumor or metastases. blood sugar and plasma insulin followed the course seen in untreated animals. The number of animals remaining free of recurrent tumor varied with the size of the probe tip used for cryonecrosis. Localized in situ tumor destruction controlled the hypersccretion of this functional endocrine malignancy." @default.
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- W2034619091 date "1972-01-01" @default.
- W2034619091 modified "2023-09-27" @default.
- W2034619091 title "Alterations of blood sugar and plasma insulin after cryosurgery of functioning islet-cell tumor" @default.
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- W2034619091 doi "https://doi.org/10.1002/jso.2930040513" @default.
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