Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034623918> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2034623918 endingPage "1029" @default.
- W2034623918 startingPage "1026" @default.
- W2034623918 abstract "Nitric oxide (NO) is involved in host defense reactions, and NO production is elevated in various inflammatory disorders. We have found very high levels of luminal NO in the urinary bladder of patients with interstitial cystitis. Oral treatment with low doses of L-arginine, the substrate for NO production, has been reported to alleviate symptoms in patients with interstitial cystitis. The aim of our investigation was to evaluate the effect of higher doses of L-arginine in patients with interstitial cystitis and to study the effects of L-arginine on NO production in the bladder.Nine women (age 69+/-3 years) with interstitial cystitis were treated daily with 3 or 10 g of L-arginine for 5 weeks. Symptoms were evaluated with an interstitial cystitis symptom score index, and NO production was measured. Patients with stress incontinence (n=18) were used as control subjects for measurement of NO levels.NO concentration in the urinary bladder was markedly elevated in the patients with interstitial cystitis (239+/-60 ppb) compared with the control patients (15+/-2 ppb). NO levels did not change in the patients with interstitial cystitis after oral treatment with L-arginine (189+/-72 ppb). There was no significant change in the symptom scores at either dose after 5 weeks of L-arginine treatment.L-arginine treatment in the doses used in this study did not change NO production in the urinary bladder in patients with interstitial cystitis. Furthermore, the patients in our study did not notice any relief of their symptoms." @default.
- W2034623918 created "2016-06-24" @default.
- W2034623918 creator A5004587560 @default.
- W2034623918 creator A5033731052 @default.
- W2034623918 creator A5079244052 @default.
- W2034623918 creator A5088377072 @default.
- W2034623918 date "1998-12-01" @default.
- W2034623918 modified "2023-10-13" @default.
- W2034623918 title "Effects of l-arginine treatment on symptoms and bladder nitric oxide levels in patients with interstitial cystitis" @default.
- W2034623918 cites W1668416847 @default.
- W2034623918 cites W1764308599 @default.
- W2034623918 cites W1947666932 @default.
- W2034623918 cites W1981029474 @default.
- W2034623918 cites W1989956955 @default.
- W2034623918 cites W2022377100 @default.
- W2034623918 cites W2049237492 @default.
- W2034623918 cites W2051847186 @default.
- W2034623918 cites W2054157046 @default.
- W2034623918 cites W2056432967 @default.
- W2034623918 cites W2058250108 @default.
- W2034623918 cites W2072715273 @default.
- W2034623918 cites W2079130657 @default.
- W2034623918 cites W2079791203 @default.
- W2034623918 cites W2086100171 @default.
- W2034623918 cites W2133373983 @default.
- W2034623918 cites W2168556036 @default.
- W2034623918 cites W2170413821 @default.
- W2034623918 doi "https://doi.org/10.1016/s0090-4295(98)00343-4" @default.
- W2034623918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9836549" @default.
- W2034623918 hasPublicationYear "1998" @default.
- W2034623918 type Work @default.
- W2034623918 sameAs 2034623918 @default.
- W2034623918 citedByCount "35" @default.
- W2034623918 countsByYear W20346239182012 @default.
- W2034623918 countsByYear W20346239182013 @default.
- W2034623918 countsByYear W20346239182018 @default.
- W2034623918 countsByYear W20346239182021 @default.
- W2034623918 crossrefType "journal-article" @default.
- W2034623918 hasAuthorship W2034623918A5004587560 @default.
- W2034623918 hasAuthorship W2034623918A5033731052 @default.
- W2034623918 hasAuthorship W2034623918A5079244052 @default.
- W2034623918 hasAuthorship W2034623918A5088377072 @default.
- W2034623918 hasConcept C126322002 @default.
- W2034623918 hasConcept C126894567 @default.
- W2034623918 hasConcept C185592680 @default.
- W2034623918 hasConcept C2777468819 @default.
- W2034623918 hasConcept C2778508898 @default.
- W2034623918 hasConcept C2779762690 @default.
- W2034623918 hasConcept C515207424 @default.
- W2034623918 hasConcept C519581460 @default.
- W2034623918 hasConcept C55493867 @default.
- W2034623918 hasConcept C71924100 @default.
- W2034623918 hasConcept C77411442 @default.
- W2034623918 hasConcept C90924648 @default.
- W2034623918 hasConceptScore W2034623918C126322002 @default.
- W2034623918 hasConceptScore W2034623918C126894567 @default.
- W2034623918 hasConceptScore W2034623918C185592680 @default.
- W2034623918 hasConceptScore W2034623918C2777468819 @default.
- W2034623918 hasConceptScore W2034623918C2778508898 @default.
- W2034623918 hasConceptScore W2034623918C2779762690 @default.
- W2034623918 hasConceptScore W2034623918C515207424 @default.
- W2034623918 hasConceptScore W2034623918C519581460 @default.
- W2034623918 hasConceptScore W2034623918C55493867 @default.
- W2034623918 hasConceptScore W2034623918C71924100 @default.
- W2034623918 hasConceptScore W2034623918C77411442 @default.
- W2034623918 hasConceptScore W2034623918C90924648 @default.
- W2034623918 hasIssue "6" @default.
- W2034623918 hasLocation W20346239181 @default.
- W2034623918 hasLocation W20346239182 @default.
- W2034623918 hasOpenAccess W2034623918 @default.
- W2034623918 hasPrimaryLocation W20346239181 @default.
- W2034623918 hasRelatedWork W2048188647 @default.
- W2034623918 hasRelatedWork W2407699338 @default.
- W2034623918 hasRelatedWork W2440458712 @default.
- W2034623918 hasRelatedWork W2463957749 @default.
- W2034623918 hasRelatedWork W2947428393 @default.
- W2034623918 hasRelatedWork W3092254707 @default.
- W2034623918 hasRelatedWork W3183072575 @default.
- W2034623918 hasRelatedWork W3215458822 @default.
- W2034623918 hasRelatedWork W4296706835 @default.
- W2034623918 hasRelatedWork W154918438 @default.
- W2034623918 hasVolume "52" @default.
- W2034623918 isParatext "false" @default.
- W2034623918 isRetracted "false" @default.
- W2034623918 magId "2034623918" @default.
- W2034623918 workType "article" @default.