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- W2034626555 abstract "A simple method is described by which the Ki value of tight binding inhibitors of enzymes can be calculated directly from the IC50 value determined from graphical analysis of dose-response curves. Experimental verification of this method is provided by study of 15 inhibitors of the enzyme stromelysis which span a broad range of Ki values. A simple method is described by which the Ki value of tight binding inhibitors of enzymes can be calculated directly from the IC50 value determined from graphical analysis of dose-response curves. Experimental verification of this method is provided by study of 15 inhibitors of the enzyme stromelysis which span a broad range of Ki values." @default.
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- W2034626555 date "1995-09-01" @default.
- W2034626555 modified "2023-10-14" @default.
- W2034626555 title "Estimating KI values for tight binding inhibitors from dose-response plots" @default.
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- W2034626555 doi "https://doi.org/10.1016/0960-894x(95)00330-v" @default.
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