FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034640612> ?p ?o ?g. }

• W2034640612 endingPage "162" @default.
• W2034640612 startingPage "149" @default.
• W2034640612 abstract "Objectives : The purpose of this study is to investigate the effects of hot pepper extract and capsaicin on the adipogenesis in 3T3-L1 cells, lipolysis in rat epididymal adipocytes and histological changes in porcine adipose tissue. Methods : Inhibiton of preadipocyte differentiation and/or stimulation of lipolysis play important roles in reducing obesity. 3T3-L1 preadipocytes were differentiated with adipogenic reagents by incubating for 3 days in the absence or presence of hot pepper extract or capsaicin ranging from 0.01 to . The effects of hot pepper extract and capsaicin on adipogenesis were examined by measuring GPDH activity and by Oil Red O staining. Mature adipocytes from rat epididymal fat pad was incubated with hot pepper extract or capsaicin ranging from 0.01 to for 3 hrs. The effects of hot pepper extract and capsaicin on lipolysis were examined by measuring free glycerol released. Fat tissue from pig skin was injected with hot pepper extract or capsaicinCFP ranging from 0.1 to to examine the effects of hot pepper extract and capsaicin on histological changes under light microscopy. Results : The following results were obtained from present study on adipogenesis of preadipocytes, lipolysis of adipocytes and histological changes in fat tissue. 1. Hot pepper extract and capsaicin inhibited adipogenic differentiation at the concentration of 0.1 and , respectively, indicating that capsaicin was more effective in inhibiting adipogenesis than hot pepper extract. 2. Hot pepper extract and capsaicin decreased the activity of glycerol-3-phosphate dehydrogenase(GPDH) at the concentration of 0.1 and , respectively, indicating that capsaicin was more effective in inhibiting adipogenic differentiation than hot pepper extract. 3. Hot pepper extract and capsaicin increased glycerol release at the concentration of . There was no difference in lipolytic activity between hot pepper extract and capsaicin at the corresponding concentration. 4. Hot pepper extract and capsaicin caused shrinkage of fat cells, resulting in cell death at the concentration of , although capsaicin exerted this action over wide area than hot pepper extract. Conclusions : These results suggest that hot pepper extract and capsaicin efficiently inhibited adipogenesis, increased lipolysis of adipocytes and caused to shrink fat cells. Future studies are needed to make use of hot pepper extract pharmacopuncture for the treatment of obesity." @default.
• W2034640612 created "2016-06-24" @default.
• W2034640612 creator A5033656032 @default.
• W2034640612 creator A5050220955 @default.
• W2034640612 creator A5071953442 @default.
• W2034640612 creator A5078553298 @default.
• W2034640612 date "2008-03-31" @default.
• W2034640612 modified "2023-09-25" @default.
• W2034640612 title "The effects of Hot Pepper Extract and Capsaicin on Adipocyte Metabolism" @default.
• W2034640612 cites W1815087127 @default.
• W2034640612 cites W1842482804 @default.
• W2034640612 cites W1993137708 @default.
• W2034640612 cites W2051325793 @default.
• W2034640612 cites W2064549818 @default.
• W2034640612 cites W2076907421 @default.
• W2034640612 cites W2118905516 @default.
• W2034640612 cites W2128635872 @default.
• W2034640612 cites W2143873575 @default.
• W2034640612 cites W2161201457 @default.
• W2034640612 cites W2170698646 @default.
• W2034640612 doi "https://doi.org/10.3831/kpi.2008.11.1.149" @default.
• W2034640612 hasPublicationYear "2008" @default.
• W2034640612 type Work @default.
• W2034640612 sameAs 2034640612 @default.
• W2034640612 citedByCount "2" @default.
• W2034640612 countsByYear W20346406122015 @default.
• W2034640612 countsByYear W20346406122019 @default.
• W2034640612 crossrefType "journal-article" @default.
• W2034640612 hasAuthorship W2034640612A5033656032 @default.
• W2034640612 hasAuthorship W2034640612A5050220955 @default.
• W2034640612 hasAuthorship W2034640612A5071953442 @default.
• W2034640612 hasAuthorship W2034640612A5078553298 @default.
• W2034640612 hasBestOaLocation W20346406121 @default.
• W2034640612 hasConcept C126322002 @default.
• W2034640612 hasConcept C170493617 @default.
• W2034640612 hasConcept C171089720 @default.
• W2034640612 hasConcept C185592680 @default.
• W2034640612 hasConcept C2776175234 @default.
• W2034640612 hasConcept C2776242653 @default.
• W2034640612 hasConcept C2780051329 @default.
• W2034640612 hasConcept C31903555 @default.
• W2034640612 hasConcept C62231903 @default.
• W2034640612 hasConcept C71924100 @default.
• W2034640612 hasConceptScore W2034640612C126322002 @default.
• W2034640612 hasConceptScore W2034640612C170493617 @default.
• W2034640612 hasConceptScore W2034640612C171089720 @default.
• W2034640612 hasConceptScore W2034640612C185592680 @default.
• W2034640612 hasConceptScore W2034640612C2776175234 @default.
• W2034640612 hasConceptScore W2034640612C2776242653 @default.
• W2034640612 hasConceptScore W2034640612C2780051329 @default.
• W2034640612 hasConceptScore W2034640612C31903555 @default.
• W2034640612 hasConceptScore W2034640612C62231903 @default.
• W2034640612 hasConceptScore W2034640612C71924100 @default.
• W2034640612 hasIssue "1" @default.
• W2034640612 hasLocation W20346406121 @default.
• W2034640612 hasLocation W20346406122 @default.
• W2034640612 hasOpenAccess W2034640612 @default.
• W2034640612 hasPrimaryLocation W20346406121 @default.
• W2034640612 hasRelatedWork W1920180984 @default.
• W2034640612 hasRelatedWork W2351796323 @default.
• W2034640612 hasRelatedWork W2363976681 @default.
• W2034640612 hasRelatedWork W2370175305 @default.
• W2034640612 hasRelatedWork W2405300154 @default.
• W2034640612 hasRelatedWork W2748952813 @default.
• W2034640612 hasRelatedWork W2892275830 @default.
• W2034640612 hasRelatedWork W2899084033 @default.
• W2034640612 hasRelatedWork W3177515055 @default.
• W2034640612 hasRelatedWork W1766626960 @default.
• W2034640612 hasVolume "11" @default.
• W2034640612 isParatext "false" @default.
• W2034640612 isRetracted "false" @default.
• W2034640612 magId "2034640612" @default.
• W2034640612 workType "article" @default.