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- W2034642305 abstract "a-Methyl-norepinephrme, norepinephrine and epinephrine stimulate the mobilization of fatty adds from epididymal fat of guinea pigs, when incubated in vitro, to the same order of magnitude. Metaraminol, however, is at least a thousand times less potent. The in vivo lipolytic potency of tyramine was investigated in guinea pigs and rats treated with metaraminol. In rats tyramine had no effect on the mobilization of fatty acids, whereas guinea pigs responded to tyramine with an additional increase of plasma fatty acids. a-Methyl-norepinephrme was found in heart tissue of guinea pigs but not in that of rats. The conversion of metaraminol into a-methyl-norepinephrine is postulated and made responsible for the ‘tyramine effect’ in the guinea pig." @default.
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- W2034642305 date "1967-08-01" @default.
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- W2034642305 title "Tyramine induced lipolysis following pretreatment of guinea pigs and rats with metaraminol" @default.
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- W2034642305 doi "https://doi.org/10.1016/0006-2952(67)90127-x" @default.
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