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- W2034643418 abstract "SUMMARY Small-cell lung cancer (SCLC) accounts for approximately 15% of all new lung cancer diagnoses. The therapeutic approach is based according to the two-stage classification: limited-stage (LS) and extensive-stage (ES) disease. In LS-SCLC, concomitant radiochemotherapy, followed in nonprogressing patients by prophylactic cranial irradiation, is the standard of care. In ES-SCLC, chemotherapy is the cornerstone treatment, followed in patients who do not progress by prophylactic cranial irradiation. Platinum/etoposide is the regimen that has been used in both stages since the 1980s. This review focuses on the current state-of-the-art treatment of LS- and ES-SCLC and on specific questions that can be addressed to improve their outcomes, and looks at possible future developments." @default.
- W2034643418 created "2016-06-24" @default.
- W2034643418 creator A5032078755 @default.
- W2034643418 date "2012-06-01" @default.
- W2034643418 modified "2023-09-27" @default.
- W2034643418 title "Small-cell lung cancer: state-of-the-art treatment" @default.
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- W2034643418 doi "https://doi.org/10.2217/lmt.12.1" @default.
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