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- W2034643550 abstract "The effect of pp′ DDT on the level of acetylcholine in the corpus striatum of rats has been determined. pp′ DDT (600 mg/kg.,orally) induced a small but significant decrease in the level of striatal acetylcholine 2 h after its administration and a maximal decrease 5 h after its administration. The animals showed tremors at 2 h, mild or moderate convulsions at 3.5 h and severe convulsions 5 h after treatment with pp′ DDT. Phenobarbitone abolished the convulsions while prominal reduced the severity of convulsions induced by pp′ DDT. The level of striatal acetylcholine in phenobarbitone- pp′ DDT treated animals was not significantly different from the control values; In promina- pp′ DDT treated animals, it was slightly but significantly reduced. Primidone neither changed the severity of convulsions nor the level of striatal acetylcholine in pp′ DDT treated animals." @default.
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- W2034643550 title "A study of the effects of certain barbiturates on the level of striatal acetylcholine and convulsions in 1,1,1-trichloro-2,2-bis(4′-chlorophenyl) ethane (pp′ DDT) treated rats" @default.
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- W2034643550 doi "https://doi.org/10.1016/s0031-6989(79)80080-6" @default.
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